- Hippo Signal Transduction Mechanisms in T Cell Immunity
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Bouchard A, Mariko M, Chang J, Panneton V, Li J, Bouklouch Y, Suh WK
- KMID: 2511857
- Immune Netw.
- 2020 Oct;20(5):e36.
- doi: 10.4110/in.2020.20.e36
Hippo signaling pathways are evolutionarily conserved signal transduction mechanisms mainly involved in organ size control, tissue regeneration, and tumor suppression. However, in mammals, the primary role of Hippo signaling seems... -
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- Host-Pathogen Dialogues in Autophagy, Apoptosis, and Necrosis during Mycobacterial Infection
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Kim JK, Silwal P, Jo EK
- KMID: 2511858
- Immune Netw.
- 2020 Oct;20(5):e37.
- doi: 10.4110/in.2020.20.e37
Mycobacterium tuberculosis (Mtb) is an etiologic pathogen of human tuberculosis (TB), a serious infectious disease with high morbidity and mortality. In addition, the threat of drug resistance in anti-TB therapy... -
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- GRIM-19 Ameliorates Multiple Sclerosis in a Mouse Model of Experimental Autoimmune Encephalomyelitis with Reciprocal Regulation of IFNγ/Th1 and IL-17A/Th17 Cells
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Moon J, Lee SH, Lee Sy, Ryu J, Jhun J, Choi J, Kim GN, Roh S, Park SH, Cho ML
- KMID: 2511864
- Immune Netw.
- 2020 Oct;20(5):e40.
- doi: 10.4110/in.2020.20.e40
The protein encoded by the Gene Associated with Retinoid-Interferon-Induced Mortality-19 (GRIM-19) is located in the mitochondrial inner membrane and is homologous to the NADH dehydrogenase 1-alpha subcomplex subunit 13 of... -
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- Type I Interferon Increases Inflammasomes Associated Pyroptosis in the Salivary Glands of Patients with Primary Sjögren's Syndrome
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Hong SM, Lee J, Jang SG, Lee J, Cho ML, Kwok SK, Park SH
- KMID: 2511862
- Immune Netw.
- 2020 Oct;20(5):e39.
- doi: 10.4110/in.2020.20.e39
Sjögren's syndrome (SS) is a chronic and systemic autoimmune disease characterized by lymphocytic infiltration in the exocrine glands. In SS, type I IFN has a pathogenic role, and recently, inflammasome... -
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- Lactoferrin Induces Tolerogenic Bone Marrow-Derived Dendritic Cells
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Park HW, Park SH, Jo HJ, Kim TG, Lee JH, Kang SG, Jang YS, Kim PH
- KMID: 2511860
- Immune Netw.
- 2020 Oct;20(5):e38.
- doi: 10.4110/in.2020.20.e38
Dendritic cells (DCs) are professional antigen-presenting cells (APCs) that initiate both T-cell responses and tolerance. Tolerogenic DCs (tDCs) are regulatory DCs that suppress immune responses through the induction of T-cell... -
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- CCAAT/enhancer binding protein β Induces Post-Switched B Cells to Produce Blimp1 and Differentiate into Plasma Cells
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Lee G, Jang E, Youn J
- KMID: 2511868
- Immune Netw.
- 2020 Oct;20(5):e42.
- doi: 10.4110/in.2020.20.e42
Long-lasting post-switched plasma cells (PCs) arise mainly from germinal center (GC) reactions, but little is known about the mechanism by which GC B cells differentiate into PCs. Based on our... -
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- Deletion Timing of Cic Alleles during Hematopoiesis Determines the Degree of Peripheral CD4+ T Cell Activation and Proliferation
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Park GY, Lee GW, Kim S, Hong H, Park JS, Cho JH, Lee Y
- KMID: 2511870
- Immune Netw.
- 2020 Oct;20(5):e43.
- doi: 10.4110/in.2020.20.e43
Capicua (CIC) is a transcriptional repressor that regulates several developmental processes. CIC deficiency results in lymphoproliferative autoimmunity accompanied by expansion of CD44hiCD62Llo effector/memory and follicular Th cell populations. Deletion of... -
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- The Progression of SARS Coronavirus 2 (SARS-CoV2): Mutation in the Receptor Binding Domain of Spike Gene
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Kim S, Lee JH, Lee S, Shim S, Nguyen TT, Hwang J, Kim H, Choi YO, Hong J, Bae S, Jhun H, Yum H, Lee Y, Chan ED, Yu L, Azam T, Kim YD, Yeom SC, Yoo KH, Kang LW, Shin KC, Kim S
- KMID: 2511866
- Immune Netw.
- 2020 Oct;20(5):e41.
- doi: 10.4110/in.2020.20.e41
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) is a positive-sense singlestranded RNA (+ssRNA) that causes coronavirus disease 2019 (COVID-19). The viral genome encodes twelve genes for viral replication and infection.... -
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