Skip Navigation
Skip to contents
Filter

ARTICLE TYPE

PUBLICATION DATE

8 results
Display

TLR10 and Its Unique Anti-Inflammatory Properties and Potential Use as a Target in Therapeutics

Fore F, Indriputri C, Mamutse J, Nugraha J

TLRs are pattern recognition receptors (PRRs) whose cytoplasmic signalling domain is similar to that of IL-1. The extracellular domain of TLRs serve as the binding site of pathogen associated molecular...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Baseline Serum Interleukin-6 Levels Predict the Response of Patients with Advanced Non-small Cell Lung Cancer to PD-1/PD-L1 Inhibitors

Kang DH, Park CK, Chung C, Oh IJ, Kim YC, Park D, Kim J, Kwon GC, Kwon I, Sun P, Shin EC, Lee JE

Although various studies on predictive markers in the use of PD-1/PD-L1 inhibitors are in progress, only PD-L1 expression levels in tumor tissues are currently used. In the present study, we...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Cereblon Deletion Ameliorates Lipopolysaccharide-induced Proinflammatory Cytokines through 5′-Adenosine Monophosphate-Activated Protein Kinase/Heme Oxygenase-1 Activation in ARPE-19 Cells

Kim YK, Chae SC, Yang HJ, An DE, Lee S, Yeo MG, Lee KJ

Cereblon (CRBN), a negative modulator of AMP-activated protein kinase (AMPK), is highly expressed in the retina. We confirmed the expression of CRBN in ARPE-19 human retinal cells by Western blotting....
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Cathelicidin-related Antimicrobial Peptide Contributes to Host Immune Responses Against Pulmonary Infection with Acinetobacter baumannii in Mice

Kang MJ, Jang AR, Park JY, Ahn JH, Lee TS, Kim DY, Jung DH, Song EJ, Hong JJ, Park JH

Acinetobacter baumannii is known for its multidrug antibiotic resistance. New approaches to treating drug-resistant bacterial infections are urgently required. Cathelicidin-related antimicrobial peptide (CRAMP) is a murine antimicrobial peptide that exerts...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Emerging Role of Eosinophils as Multifunctional Leukocytes in Health and Disease

Kim HJ, Jung Y

Eosinophils are terminally differentiated cytotoxic effector cells that have a role in parasitic infections and allergy by releasing their granule-derived cytotoxic proteins. However, an increasing number of recent observations indicate...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Biomarkers and Associated Immune Mechanisms for Early Detection and Therapeutic Management of Sepsis

Trzeciak A, Pietropaoli AP, Kim M

Sepsis is conceptually defined as life-threatening organ dysfunction that is caused by a dysregulated host response to infection. Although there has been significant advancement in recent decades in defining and...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Deciphering Macrophage Phenotypes upon Lipid Uptake and Atherosclerosis

Lee J, Choi JH

In the progression of atherosclerosis, macrophages are the key immune cells for foam cell formation. During hyperlipidemic condition, phagocytic cells such as monocytes and macrophages uptake oxidized low-density lipoproteins (oxLDLs)...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Roles of CCR7 for the Homing of Memory CD8+ T Cells into Their Survival Niches

Choi H, Song H, Jung YW

Memory CD8+ T cells in the immune system are responsible for the removal of external Ags for a long period of time to protect against re-infection. Naïve to memory CD8+...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2021 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr