- Extracellular Vesicles of Neutrophils
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Hong CW
- KMID: 2429835
- Immune Netw.
- 2018 Dec;18(6):e43.
- doi: 10.4110/in.2018.18.e43
Extracellular vesicles (EVs) are membrane-derived vesicles that mediate intercellular communications. As professional phagocytes, neutrophils also produce EVs in response to various inflammatory stimuli during inflammatory processes. Neutrophil-derived EVs can be... -
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- Regulatory Roles of the Caspase-11 Non-Canonical Inflammasome in Inflammatory Diseases
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Yi YS
- KMID: 2429833
- Immune Netw.
- 2018 Dec;18(6):e41.
- doi: 10.4110/in.2018.18.e41
Inflammation is an immune response mediated by innate immune cells of tissues, against invading microbes and cellular stress. The hallmark of inflammatory responses is the activation of inflammasomes — multiprotein... -
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- Two-Round Mixed Lymphocyte Reaction for Evaluation of the Functional Activities of Anti-PD-1 and Immunomodulators
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Kwon M, Choi YJ, Sa M, Park SH, Shin EC
- KMID: 2429837
- Immune Netw.
- 2018 Dec;18(6):e45.
- doi: 10.4110/in.2018.18.e45
Immune checkpoint inhibitors (ICIs), such as anti-PD-1 and anti-PD-L1 Abs, have shown efficacy for the treatment of various cancers. Although research has actively sought to develop new ICIs and immunomodulators,... -
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- From Bench to Clinic: the Potential of Therapeutic Targeting of the IL-22 Signaling Pathway in Atopic Dermatitis
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Jin M, Yoon J
- KMID: 2429834
- Immune Netw.
- 2018 Dec;18(6):e42.
- doi: 10.4110/in.2018.18.e42
Atopic dermatitis (AD) is the most common pruritic inflammatory skin disease characterized by thickening of epidermis and dermis as well as by the infiltration of multiple pathogenic polarized T lymphocytes,... -
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- Heat-Killed Saccharomyces cerevisiae, A Dectin-1 Agonist, Selectively Induces IgG4 Production by Human B Cells
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Park HY, Yoon HK, Kim JY, Park SR
- KMID: 2429838
- Immune Netw.
- 2018 Dec;18(6):e46.
- doi: 10.4110/in.2018.18.e46
Dectin-1 is a major receptor that recognizes fungal cell wall β-glucan. We previously reported that heat-killed Saccharomyces cerevisiae (HKSC), a Dectin-1 agonist, selectively induces IgG1 class switching in mouse B... -
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- Obesity-Induced Peritoneal Dissemination of Ovarian Cancer and Dominant Recruitment of Macrophages in Ascites
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Ignacio RM, Lee ES, Wilson AJ, Beeghly-Fadiel A, Whalen MM, Son DS
- KMID: 2429839
- Immune Netw.
- 2018 Dec;18(6):e47.
- doi: 10.4110/in.2018.18.e47
One-fifth of cancer deaths are associated with obesity. Because the molecular mechanisms by which obesity affects the progression of ovarian cancer (OC) are poorly understood, we investigated if obesity could... -
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- Skewed Dendritic Cell Differentiation of MyD88-Deficient Donor Bone Marrow Cells, Instead of Massive Expansion as Myeloid-Derived Suppressor Cells, Aggravates GVHD
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Lee YK, Ju JM, Shon WJ, Oh S, Min CK, Kang MS, Shin DM, Choi EY
- KMID: 2429836
- Immune Netw.
- 2018 Dec;18(6):e44.
- doi: 10.4110/in.2018.18.e44
Graft-versus-host disease (GVHD), a life-threatening complication after bone marrow transplantation (BMT), is induced by activation of alloreactive donor T cells. Our previous study demonstrated that transplantation of myeloid differentiation factor... -
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