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Expression of the ATP-gated P2X7 Receptor on M Cells and Its Modulating Role in the Mucosal Immune Environment

Kim SH, Lee HY, Jang YS

Interactions between microbes and epithelial cells in the gastrointestinal tract are closely associated with regulation of intestinal mucosal immune responses. Recent studies have highlighted the modulation of mucosal immunity by...
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Lactoferrin Combined with Retinoic Acid Stimulates B1 Cells to Express IgA Isotype and Gut-homing Molecules

Kang SH, Jin BR, Kim HJ, Seo GY, Jang YS, Kim SJ, An SJ, Park SR, Kim WS, Kim PH

It is well established that TGF-beta1 and retinoic acid (RA) cause IgA isotype switching in mice. We recently found that lactoferrin (LF) also has an activity of IgA isotype switching...
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Protection Against Salmonella Typhimurium, Salmonella Gallinarum, and Salmonella Enteritidis Infection in Layer Chickens Conferred by a Live Attenuated Salmonella Typhimurium Strain

Lee JH

In the present study, we investigated the protection conferred by a live attenuated Salmonella enterica serovar Typhimurium (ST) strain against Salmonella Typhimurium, Salmonella Gallinarum (SG), and Salmonella Enteritidis (SE) infection...
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Immune Cells in the Female Reproductive Tract

Lee SK, Kim CJ, Kim DJ, Kang JH

The female reproductive tract has two main functions: protection against microbial challenge and maintenance of pregnancy to term. The upper reproductive tract comprises the fallopian tubes and the uterus, including...
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A Molecular Mucosal Adjuvant To Enhance Immunity Against Pneumococcal Infection In The Elderly

Fukuyama Y, Ikeda Y, Ohori J, Sugita G, Aso K, Fujihashi , Briles DE, McGhee JR, Fujihashi

Streptococcus pneumoniae (the pneumococcus) causes a major upper respiratory tract infection often leading to severe illness and death in the elderly. Thus, it is important to induce safe and effective...
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Regulation of Intestinal Immune System by Dendritic Cells

Ko HJ, Chang SY

Innate immune cells survey antigenic materials beneath our body surfaces and provide a front-line response to internal and external danger signals. Dendritic cells (DCs), a subset of innate immune cells,...
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