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Expression of Toll-like Receptors 2 and 4 and Immunoglobulins in Children wih Recurrent Otitis Media with Effusion

Cha CI, Lee YC, Park DC, Kim YI, Lee JW, Yeo SG

BACKGROUND: Toll-like receptors (TLRs) detect microbial infection and can directly induce innate host defense responses, which are thought to play critical roles in protecting the tubotympanum from infection. However, little...
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Expression of Gpnmb in NK Cell Development from Hematopoietic Stem Cells

Shin N, Lee J, Lee J, Jeong M, Kim MS, Lee SH, Yoon SR, Chung JW, Kim TD, Choi I

BACKGROUND: Molecular mechanisms of natural killer (NK) cell development from hematopoietic stem cells (HSCs) have not been clearly elucidated, although the roles of some genes in NK cell development have...
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Oral Tolerance Increased the Proportion of CD8+ T Cells in Mouse Intestinal Lamina Propria

Cho KA, Cha JE, Woo SY

BACKGROUND: Oral tolerance is defined by the inhibition of immune responsiveness to a protein previously exposed via the oral route. Protein antigens exposed via the oral route can be absorbed...
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Sepsis Mortality in CIITA Deficient Mice is Associated with Excessive Release of High-mobility Group Box 1

Kim JY, Kim JH, Seo JN, Oh KI

BACKGROUND: Down regulation of major histocompatibility complex class II transactivator (CIITA) has been identified as a major factor of immunosuppression in sepsis and the level of CIITA expression inversely correlates...
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