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Immune Responses to Viral Infection

Hwang ES, Park CG, Cha CY

Viruses are obligate intracellular parasites which cause infection by invading and replicating within cells. The immune system has mechanisms which can attack the virus in extracellular and intracellular phase of...
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The Effect of Mesenchymal Stem Cells on the Activation of Dendritic Cells in the Cell Culture Insert System

Kim KW, Park SY, Lee KB, Kim HS

BACKGROUND: Bone marrow mesenchymal stem cells (MSC) inhibit the immune response of lymphocytes to specific antigens and dendritic cells (DC) are professional antigen- presenting cells whose function is to present...
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Inhibitory Effect of Rubus Coreanus on Compound 48/80- or Anti-DNP IgE-Induced Mast Cell Activation

Li GZ, Chai OH, Song CH

BACKGROUND: The fruit of Rubus coreanus (RC), a perennial herb, has been cultivated for a long time as a popular vegetable. The anti-allergy mechanism of RC is unknown. The purpose...
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Effects of Nitric Oxide on the Induction of Experimental Allergic Orchitis in Guinea Pig

An JH, Kim IK, Kim TS, Kwak HJ, Rhew HY, Chung HT

BACKGROUND: Production of nitric oxide (NO) by inducible NO synthase (iNOS) has been implicated in the pathology of autoimmune disease. It is unknown whether iNOS expression is increased within testes...
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LIGHT is Expressed in Foam Cells and Involved in Destabilization of Atherosclerotic Plaques through Induction of Matrix Metalloproteinase-9 and IL-8

Kim WJ, Lee WH

BACKGROUND: LIGHT (TNFSF14) is a member of tumor necrosis factor superfamily and is the ligand for TR2 (TNFRSF14/HVEM). LIGHT is known to have pro- inflammatory roles in atherosclerosis. METHODS: To...
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Comparison between Immunostimulatory Activity and Molecular Structure of Different Polysaccharides

Shim JY, Jung IS, Kim CW, Yun YS, Song JY

BACKGROUND: We previously reported that ginsan, a polysaccharide extracted from Panax ginseng had an immunostimulatory activity such as mitogenic activity, activation of macrophages and killer cells, and production of a...
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Antigen Nonspecific Death of Immature Thymocytes by Corticosteroids and TNF

Oh K, Surh CD, Cho J, Lee DS

BACKGROUND: In the thymus, developing thymocytes continually interact with thymic epithelial cell components. Self MHC restriction of mature T cells are imposed in the thymus through interaction of immature double...
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