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Enhancement of the Stability and Skin Penetration of Vitamin C by Polyphenol

Kang JS, Cho D, Lee WJ

BACKGROUND: It is necessary for human beings to uptake vitamin C through diet or supplements. It is also well-known that vitamin C plays an important role in the prevention of...
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Enhancement of Cell Migration by Corticotropin-Releasing Hormone (CRH) in Human Gastric Cancer Cell Line, MKN-28

Cheon S, Cho D

BACKGROUND: Corticotropin-Releasing Hormone (CRH), an important regulator of stress response, has a potent immunoregulatory effect with the ability to promote the growth of various cancer through CRH receptor type 1...
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Gene Expression Changes Associated with Sustained p16 Expression in Hepatocellular Carcinoma Cells

Oh SJ, Im JY, Jung CH, Lee YB

BACKGROUND: The normal functions of the cell cycle inhibitor p16INK4a are frequently inactivated in many human cancers. Over 80% of hepatocellular carcinoma (HCC) cases lack a functional p16/Rb pathway. p16/Rb...
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Potentiality of Anti-idiotypic Antibodies Mimicking GD2 to Induce Cellular Immunity

Park YS, Shin WS

BACKGROUND: Disialoganglioside GD2 is a tumor-associated antigen that is overexpressed on tumor cells of neuroectodermal origin, such as melanoma, small cell lung carcinoma and neuroblastoma. Immunity against GD2 has anti-tumor...
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IFN-gamma Regulates Expression of BRG1 Associated Factor 155/170 and Sensitivity to Steroid in Astrocytes

Lim JH, Lee J, Park JY, Choi IH

BACKGROUND: The expression of BRG1 associated factors (BAF) 155 and BAF 170 in response to IFN-gamma or TNF-alpha was studied in astrocytoma cell lines and primary astrocytes. BAFs are complexed...
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Characterization of Mouse B Lymphoma Cells (CH12F3-2A) for the Study of IgA Isotype Switching

Jang YS, Choi SH, Park SR, Kim HA, Park JB, Kim PH

BACKGROUND: It is well known that IgA isotype switching is induced by TGF-beta1. LPS-activated mouse normal B cells well differentiate into IgA secreting plasma cells under the influence of TGF-beta1....
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The Emerging Role of Natural Killer Cells in Innate and Adaptive Immunity

Kim EM, Ko CB, Myung PK, Cho D, Choi I, Kang HS

In the early host defense system, effector function of natural killer (NK) cells results in natural killing against target cells such as microbe-infected, malignant, and certain allogenic cells without prior...
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