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Characterization of the Monoclonal Antibody Specific to Human S100A6 Protein

Kim JW, Yoon SY, Joo JH, Kang HB, Lee YH, Choe YK, Choe IS

BACKGROUND: S100A6 is a calcium-binding protein overexpressed in several tumor cell lines including melanoma with high metastatic activity and involved in various cellular processes such as cell division and differentiation....
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Differentiation of Osteoblast Progenitor Cells from Human Umbilical Cord Blood

Hong SJ, Lee EA, Chae GT, Han H

BACKGROUND: Human umbilical cord bloods, which could be taken during the delivery are utilized as a source of hematopoietic stem cells. Also in cord blood, there are several kinds of...
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A Murine Model of Toluene Diisocyanate-induced Contact Hypersensitivity

Chai OH, Park SG, Sohn JS, Hwang SS, Li GZ, Han EH, Kim HT, Lee MS, Lee HK, Lee YC, Song CH

BACKGROUND: Toluene diisocyanate (TDI) can cause contact allergy and occupational asthma, but the mechanism underlying sensitization to this chemical compound remains controversal. Also the correlation of mast cell with contact...
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A Human Immunodeficiency Virus Type 1 (HIV-1) Tat Cofactor Absent in Rodent Cells is a TAR-associated Factor

Lee IS, Shank PR

BACKGROUND: Although Tat plays a role as a potent transactivator in the viral gene expression from the Human Immunodeficiency Virus type 1 long terminal repeat (HIV-1 LTR), it does not...
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CD40-CD40 Ligand Interactions in the Production of IL-12 and IFN-gamma by Tuberculous Pleural Mononuclear Cells

Song CH, Nam HH, An JO, Lee JS, Kim HJ, Park JK, Suhr JW, Jung SS, Na MJ, Paik TH, Jo EK

BACKGROUND: Our previous study showed that purified protein derivative (PPD)- stimulated pleural mononuclear cells (PMC) from tuberculous pleurisy (Tbp) produced significantly more IFN-gamma (10- to 70-fold) after in vitro PPD...
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Identification of a Variant Form of Cellular Inhibitor of Apoptosis Protein (c-IAP2) That Contains a Disrupted Ring Domain

Park SM, Kim JS, Park JH, Kang SG, Lee TH

Among the members of the inhibitor of apoptosis (IAP) protein family, only Livin and survivin have been reported to have variant forms. We have found a variant form of c-IAP2...
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Alloimmune and Skin Allograft Responses in 4-1BB (CD137)-deficient Mice

Wolisi G, Srirangam , Vinay DS, Suh JH, Suh HS, Choi BK, Kwon BS

BACKGROUND: The costimulatory molecule 4-1BB, a member of nerve growth factor receptor/tumor necrosis factor (NGFR/TNFR) super family, is involved in cell survival and death. METHODS: In this study, female C57BL/6 (H-2(b))...
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Protein Interaction Databases and Its Application

Kim MK, Park HS

In the past, bioinformatics was often regarded as a difficult and rather remote field, practiced only by computer scientists and not a practical tool available to biologists. However, the various...
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