Skip Navigation
Skip to contents
Filter

ARTICLE TYPE

PUBLICATION DATE

11 results
Display

Family Study of TAP Gene Polymorphism and HLA-TAP Haplotypes in Koreans

Whang DH, Park MH

BACKGROUND: TAP1 and TAP2 are two ABC transporter genes located within the class II region of the human MHC. Their protein products form a heterodimer whose function is to transport...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Polymorphisms in the TNF-alpha Gene and Extended HLA and TNF-alpha Haplotypes in Koreans

Park YJ, Park HJ, Park MH

BACKGROUND: Tumor necrosis factor-alpha (TNF-alpha) is known to play an important role in various conditions such as inflammation, autoimmunity, apoptosis, insulin resistance and sleep induction. Five single nucleotide polymorphisms (SNPs)...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Isolation of Mouse Ig Heavy and Light Chain Genomic DNA Clones, and Construction of Gene Knockout Vector for the Generation of Humanized Xenomouse

Lee HK, Cha SH

BACKGROUND: Monoclonal antibodies (mAb) of rodent origin are produced with ease by hybridoma fusion technique, and have been successfully used as therapeutic reagents for humans after humanization by genetic engineering....
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Association of HLA-DRB1 and DQB1 Alleles and a Study of Anticardiolipin Antibody and Anti-beta2 Glycoprotein I Antibody in Korean SLE Patients

Lee SG, Cha HS, Yang YS

BACKGROUND: Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by diverse clinical manifestations and autoantibody production, which is known to be strongly influenced by genetic factors. Previous studies...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Serum Levels of Type 2 Chemokines in Lepromatous Leprosy Patients

Lew W, Nakamura K, Tada Y, Kwahck H, Chang SK, Tamaki K

BACKGROUND: The type 2 deviated immunological state is predominant in lepromatous leprosy. Erythema nodosum leprosum (ENL) is an immune-complex mediated reaction that typically occurs in lepromatous leprosy. To date, the...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Differential Staging of Murine Thymic Lymphoma Cell Lines, Scid.adh, R1.1 and EL-4

Chae JS, Kim HJ, Park WS, Bae Y, Jung KC

BACKGROUND: Scid.adh is a recently developed murine thymic lymphoma cell line, which has been used as in vitro model for the study of double negative stage III thymocytes. In this...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Suppressed DNA Repair Mechanisms in Rheumatoid Arthritis

Lee SH, Firestein

BACKGROUND: Reactive oxygen and nitrogen are produced by rheumatoid arthritis (RA) synovial tissue and can induce mutations in key genes. Normally, this process is prevented by a DNA mismatch repair...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Production of Plasma Leptin and Expression of Interferon-gamma Inducible Protein-10 (IP-10), Monokine Induced by Interferon-gamma (Mig) and Interleukin-8 (IL-8) mRNA in Kawasaki Disease

Lee YH, Kim WD, Kim HS

BACKGROUND: Kawasaki disease is an acute febrile illness with systemic vasculitis which primarily affects children, We examined the production of leptin in plasma and gene expressions of CXC chemokines in...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Identification of Functionally Different Rat IgE in RBL-2H3 Exocytosis

Kim JS, Cho S, Joo KH, Lee JS, Conrad DH, Cho SW

BACKGROUND: IgE is closely related to the development of allergies. However, the poor relationship between the specific IgE level and the severity of allergic diseases suggests the possibility of functionally...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Psoriasis as a T-cell-mediated Immunologic Disease

Lew W

Although the exact mechanism responsible for the pathogenesis of psoriasis is unclear, interferon-gamma producing type 1 T cells have been reported to play a significant role. Infiltrating activated type 1...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Telomerase: Key to Mortal or Immortal Road

Yang EY, Sung YH, Lee HW

Gradual attrition of telomere to a critical short length elicits successive cellular response of cellular senescence and crisis. Cancer cells evade this process by maintaining functional telomeres via one of...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2021 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr