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Implication of Egr-1 in trifluoperazine-induced growth inhibition in human U87MG glioma cells

Shin SY, Kim CG, Hong DD, Kim JH, Lee YH

  • KMID: 1094083
  • Exp Mol Med.
  • 2004 Aug;36(4):380-386.
The early growth response gene-1 (Egr-1) is a tumor suppressor which plays an important role in cell growth, differentiation and apoptosis. Egr-1 has been shown to be down-regulated in many...
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B-cell translocation gene 2 positively regulates GLP-1-stimulated insulin secretion via induction of PDX-1 in pancreatic beta-cells

Hwang SL, Kwon O, Kim SG, Lee IK, Kim YD

  • KMID: 2154244
  • Exp Mol Med.
  • 2013 May;45(5):e25.
Glucagon-like peptide-1 (GLP-1) is a potent glucoincretin hormone and an important agent for the treatment of type 2 diabetes. Here we demonstrate that B-cell translocation gene 2 (BTG2) is a...
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Monocrotaline-induced pulmonary hypertension correlates with upregulation of connective tissue growth factor expression in the lung

Lee YS, Byun J, Kim JA, Lee JS, Kim KL, Suh YL, Kim JM, Jang HS, Lee JY, Shin IS, Suh W, Jeon ES, Kim DK

  • KMID: 1033098
  • Exp Mol Med.
  • 2005 Feb;37(1):27-35.
Pulmonary hypertension (PH) is characterized by structural and functional changes in the lung including proliferation of vascular smooth muscle cells (VSMCs) and excessive collagen synthesis. Although connective tissue growth factor...
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