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Molecular Mechanism of Reactive Oxygen Species-dependent ASK1 Activation in Innate Immunity

Yamauchi S, Noguchi T, Ichijo H

Apoptosis signal-regulating kinase 1 (ASK1), a mitogen- activated protein kinase kinase kinase, plays pivotal roles in stress responses. In addition, ASK1 has emerged as a key regulator of immune responses...
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