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In vitro maturation using αMEM with reduced NaCl enhances maturation and developmental competence of pig oocytes after somatic cell nuclear transfer

Lee Y, Lee J, Hyun SH, Lee GS, Lee E

Background: Compared to medium containing 108 mM sodium chloride (NaCl), in vitro maturation (IVM) using a simple medium with reduced (61.6 mM) NaCl increases the cytoplasmic maturation and embryonic development of...
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An Optimization of AAV-82Q-Delivered Rat Model of Huntington’s Disease

So KH, Choi JH, Islam J, KC E, Moon HC, Won SY, Kim HK, Kim S, Hyun SH, Park YS

Objective : No optimum genetic rat Huntington model both neuropathological using an adeno-associated virus (AAV-2) vector vector has been reported to date. We investigated whether direct infection of an AAV2...
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Diagnostic Performance of ¹⁸F-Fluorodeoxyglucose Positron Emission Tomography/CT for Chronic Empyema-Associated Malignancy

Cheon M, Yoo J, Hyun SH, Lee KS, Kim H, Kim J, Zo JI, Shim YM, Choi JY

OBJECTIVE: The purpose of this study was to evaluate the diagnostic performance of ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography (¹⁸F-FDG PET/CT) for chronic empyema-associated malignancy (CEAM). MATERIALS AND METHODS: We retrospectively reviewed...
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Development of Predictive Models in Patients with Epiphora Using Lacrimal Scintigraphy and Machine Learning

Park YJ, Bae JH, Shin MH, Hyun SH, Cho YS, Choe YS, Choi JY, Lee KH, Kim BT, Moon SH

PURPOSE: We developed predictive models using different programming languages and different computing platforms for machine learning (ML) and deep learning (DL) that classify clinical diagnoses in patients with epiphora. We...
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Production of transgenic pigs using a pGFAP-CreER(T2)/EGFP(LoxP) inducible system for central nervous system disease models

Hwang SU, Eun K, Yoon JD, Kim H, Hyun SH

Transgenic (TG) pigs are important in biomedical research and are used in disease modeling, pharmaceutical toxicity testing, and regenerative medicine. In this study, we constructed two vector systems by using...
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Clinical Significance of Incidental Focal ¹⁸F-FDG Uptake in the Spinal Cord of Patients with Cancer

Lim CH, Hyun SH, Moon SH, Cho YS, Choe YS, Lee KH, Kim BT, Choi JY

PURPOSE: We investigated the incidence, location, and clinical significance of focal ¹⁸F-FDG uptake of the spinal cord in patients with cancer. METHODS: We reviewed the medical records of 22,937 consecutive adult...
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Oocyte maturation under a biophoton generator improves preimplantation development of pig embryos derived by parthenogenesis and somatic cell nuclear transfer

Lee J, Shin H, Lee W, Lee ST, Lee GS, Hyun SH, Lee E

This study was conducted to determine the effects of biophoton treatment during in vitro maturation (IVM) and/or in vitro culture (IVC) on oocyte maturation and embryonic development in pigs. An...
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Rapamycin treatment during in vitro maturation of oocytes improves embryonic development after parthenogenesis and somatic cell nuclear transfer in pigs

Lee J, Park JI, Yun JI, Lee Y, Yong H, Lee ST, Park CK, Hyun SH, Lee GS, Lee E

This study was conducted to investigate the effects of rapamycin treatment during in vitro maturation (IVM) on oocyte maturation and embryonic development after parthenogenetic activation (PA) and somatic cell nuclear...
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Isolation and Identification of Yeasts from Wild Flowers Collected around Jangseong Lake in Jeollanam-do, Republic of Korea, and Characterization of the Unrecorded Yeast Bullera coprosmaensis

Han SM, Hyun SH, Lee HB, Lee HW, Kim HK, Lee JS

Several types of yeasts were isolated from wild flowers around Jangseong Lake in Jeollanam-do, Republic of Korea and identified by comparing the nucleotide sequences of the PCR amplicons for the...
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Evaluation of conservation of endangered species through somatic cell nuclear technology

Hyun SH, Jeong YW, Hwang KC, Lee GJ, Yang IS

The number of wild animal species is gradually decreasing due to poaching, hunting and habitat loss. While several endangered animal species have been successfully preserved at the zoo, assisted reproductive...
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Characterization of an Anti-gout Xanthine Oxidase Inhibitor from Pleurotus ostreatus

Jang IT, Hyun SH, Shin JW, Lee YH, Ji JH, Lee JS

We selected Pleurotus ostreatus from among several edible mushrooms because it has high anti-gout xanthine oxidase (XOD) inhibitory activity. The maximal amount of XOD inhibitor was extracted when the Pleurotus...
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The Initial Factors Influencing Successful Final Stereoacuity in Refractive Accommodative Esotropia

Hyun SH, Paik HJ

  • KMID: 2338739
  • J Korean Ophthalmol Soc.
  • 2014 Jun;55(6):877-881.
PURPOSE: To evaluate the initial factors influencing successful final stereoacuity in patients with refractive accommodative esotropia. METHODS: The charts of 48 refractive accommodative esotropia patients 2 years of age or older...
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Microbiological Characteristics and Physiological Functionality of New Records of Yeasts from Wild Flowers in Yokjido, Korea

Hyun SH, Lee JS

  • KMID: 2312746
  • Mycobiology.
  • 2014 Jun;42(2):198-202.
Two new yeast records, Cryptococcus adeliensis YJ19-2 and Cryptococcus uzbekistanensis YJ10-4 were screened from 60 yeasts strains that were isolated and identified from wild flowers in Yokjido, Gyeongsangnam-do, Korea. The...
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A Case of Episcleritis as a Manifestation of Neurosyphilis

Hyun SH, Lee DY, Nam DH

PURPOSE: To report a rare case of episcleritis as the only manifestation of neurosyphilis. CASE SUMMARY: A 40-year-old female was referred to the outpatient clinic because of right episcleritis that was...
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Diffuse Thyroid Uptake Incidentally Found on 18F-Fluorodeoxyglucose Positron Emission Tomography in Subjects without Cancer History

Lee JY, Choi JY, Choi YH, Hyun SH, Moon SH, Jang SJ, Choe YS, Lee KH, Kim BT

OBJECTIVE: We investigated the clinical significance of incidental diffuse thyroid uptake (DTU) on 18F-FDG PET in subjects without a history of cancer. MATERIALS AND METHODS: This study included 2062 studies from...
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Prognostic Significance of Volume-Based PET Parameters in Cancer Patients

Moon SH, Hyun SH, Choi JY

Accurate prediction of cancer prognosis before the start of treatment is important since these predictions often affect the choice of treatment. Prognosis is usually based on anatomical staging and other...
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Prognostic Value of Volume-Based 18F-Fluorodeoxyglucose PET/CT Parameters in Patients with Clinically Node-Negative Oral Tongue Squamous Cell Carcinoma

Lee SJ, Choi JY, Lee HJ, Baek CH, Son YI, Hyun SH, Moon SH, Kim BT

OBJECTIVE: To evaluate the prognostic value of volume-based metabolic parameters measured with 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) in patients with clinically node-negative (cN0) oral tongue squamous cell carcinoma (OTSCC)...
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Clinical Analysis of Puffer Fish Poisoning Cases

Hyun SH, Sohn CH, Ryoo SM, Oh BJ, Lim KS

  • KMID: 2101642
  • J Korean Soc Clin Toxicol.
  • 2011 Dec;9(2):95-100.
PURPOSE: Ingestion of puffer fish can be poisonous due to the presence of potent neurotoxins such as tetrodotoxin (TTX) found in its tissues. There are few clinical reports related to...
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Incidental Focal 18F-FDG Uptake in the Prostate: Clinical Significance and Differential Diagnostic Criteria

Cho SK, Choi JY, Yoo J, Cheon M, Lee JY, Hyun SH, Lee EJ, Lee KH, Kim BT

  • KMID: 1447595
  • Nucl Med Mol Imaging.
  • 2011 Sep;45(3):192-196.
PURPOSE: The extent and intensity of 18F-FDG uptake in prostate cancer patients are known to be variable, and the clinical significance of focal 18F-fluorodeoxyglucose (18F-FDG) uptake that is incidentally found...
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Erratum: Risk Factors Influencing Decline of Residual Renal Function in Patients on Continuous Ambulatory Peritoneal Dialysis

Kim GH, Hyun SH, Seo HJ, Choi JY, Cho JH, Kim CD, Park SH, Kim YL

  • KMID: 2307148
  • Korean J Nephrol.
  • 2011 Jan;30(1):129-129.
No abstract available.
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