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A Case of Osteomalacia Related to Adefovir in a Patient with Chronic Hepatitis B

Ahn SY, Ko SY, Jang YM, Choi YH, Kim BK, Choe WH, Lee CH, Kwon SY

Adefovir dipivoxil, an acyclic nucleoside analogue, has been approved for the treatment of patients with chronic hepatitis B. This agent is efficacious particularly in those who have developed lamivudine resistance....
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A case of severe hypophosphatemia related to adefovir dipivoxil treatment in a patient with liver cirrhosis related to hepatitis B virus

Lee HJ, Choi JW, Kim TN, Eun JR

Adefovir dipivoxyl (ADV) effectively suppresses hepatitis B virus (HBV) replication but exhibits nephrotoxicity with severe hypophosphatemia when administered at a high dosage. This is the first report of severe hypophosphatemic...
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