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Drug Hypersensitivity to Previously Tolerated Phenytoin by Carbamazepine-induced DRESS Syndrome

Kim CW, Choi GS, Yun CH, Kim DI

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome associated with anticonvulsant drugs is a rare but potentially life-threatening disease that occurs in response to arene oxide producing anticonvulsant such...
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Oral provocation tests with aspirin and food additives in asthmatic patients

Hong SP, Park HS, Lee MK, Hong CS

Aspirin and food additives are known to induce bronchoconstriction, angioedema or urticaria in susceptible patients. To evaluate the incidence of hypersensitivity to aspirin and food additives, 36 subjects with...
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Allergic Asthma and Rhinitis Caused by Household Rabbit Exposure: Identification of Serum-Specific IgE and Its Allergens

Choi JH, Kim HM, Park HS

Although rabbits are common domestic pets, severe respiratory allergic reactions to rabbits in households are unusual. Ory c 1, a 17-kDa glycoprotein found in saliva and fur, has previously been...
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New era for mucosal mast cells: their roles in inflammation, allergic immune responses and adjuvant development

Kurashima , Kiyono H

To achieve immune homeostasis in such a harsh environment as the intestinal mucosa, both active and quiescent immunity operate simultaneously. Disruption of gut immune homeostasis leads to the development of...
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Chitin, Chitinases and Chitinase-like Proteins in Allergic Inflammation and Tissue Remodeling

Lee CG

Chitin, the second most abundant polysaccharide in nature after cellulose, consist exoskeleton of lower organisms such as fungi, crustaceans and insects except mammals. Recently, several studies evaluated immunologic effects of...
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Mast Cells in Allergic Asthma and Beyond

Reuter S, Stassen M, Taube C

Mast cells have been regarded for a long time as effector cells in IgE mediated type I reactions and in host defence against parasites. However, they are resident in all...
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Skin reactivity and specific IgE antibody to two nonbiting midges in Korean respiratory allergy patients

Kim YJ, Park HS

To evaluate the significance of chironomid as a respiratory allergen, we performed skin prick tests with Chironomus plumosus (CP) and Tokunagayusurika akamusi (TA) extracts on 475 respiratory allergy patients, and...
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Molecular Approach to Allergy Diagnosis and Therapy

Ferreira F, Wolf M, Wallner M

Presently, allergy diagnosis and therapy procedures are undergoing a transition phase in which allergen extracts are being step-by-step replaced by molecule-based products. The new developments will allow clinicians to obtain...
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A 24 kDa Excretory-Secretory Protein of Anisakis simplex Larvae Could Elicit Allergic Airway Inflammation in Mice

Park HK, Cho MK, Park MK, Kang SA, Kim YS, Kim KU, Lee MK, Ock MS, Cha HJ, Yu HS

We have reported that a 24 kDa protein (22U homologous; As22U) of Anisakis simplex larvae could elicit several Th2-related chemokine gene expressions in the intestinal epithelial cell line which means...
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IgE Binding Reactivity of Peptide Fragments of Bla g 4, a Major German Cockroach Allergen

Shin KH, Jeong KY, Hong CS, Yong TS

Cockroaches have been recognized as a major cause of asthma. Bla g 4 is one of the most important German cockroach allergens. The aim of this study is to investigate...
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Effect of Cosensitization with Buckwheat Flour Extract on the Production of House Dust Mite-specific IgE

Shin YH, Sohn MH, Oh S, Lee KE, Yong TS, Park JW, Hong CS, Kim KE, Lee SY

There are studies reporting food sensitization in infancy increases the risk of sensitization to inhalants later in life. We performed a study to evaluate whether cosensitization with buckwheat (BW) has...
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