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Descriptive Epidemiology and Survival Analysis of Prolactinomas and Cushing’s Disease in Korea

Park JS, Yun SJ, Lee JK, Park SY, Chin SO

Background: Only a few studies have established the epidemiology of prolactinoma and Cushing’s disease in Korea. Furthermore, the incidence of these disease are increasing than before associated with the development...
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Recent Advances in the Development of Novel Drug Candidates for Regulating the Secretion of Pulmonary Mucus

Li X, Jin F, Lee HJ, Lee CJ

Hypersecretion of pulmonary mucus is a major pathophysiological feature in allergic and inflammatory respiratory diseases including asthma and chronic obstructive pulmonary disease (COPD). Overproduction and/or oversecretion of mucus cause the...
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Luteolin reduces fluid hypersecretion by inhibiting TMEM16A in interleukin-4 treated Calu-3 airway epithelial cells

Kim HJ, Woo J, Nam YR, Seo Y, Namkung W, Nam JH, Kim WK

Rhinorrhea in allergic rhinitis (AR) is characterized by the secretion of electrolytes in the nasal discharge. The secretion of Cl– and HCO3 – is mainly regulated by cystic fibrosis transmembrane...
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Recent Progress in the Medical Therapy of Pituitary Tumors

Langlois F, McCartney , Fleseriu M

Management of pituitary tumors is multidisciplinary, with medical therapy playing an increasingly important role. With the exception of prolactin-secreting tumors, surgery is still considered the first-line treatment for the majority...
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Clinical Guidelines for the Diagnosis and Treatment of Cushing's Disease in Korea

Hur KY, Kim JH, Kim BJ, Kim MS, Lee EJ, Kim SW

Cushing's disease (CD) is a rare disorder characterized by the overproduction of adrenocorticotropic hormone due to a pituitary adenoma that ultimately stimulates excessive cortisol secretion from the adrenal glands. Prior...
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Long-term follow-up on Cushing disease patient after transsphenoidal surgery

Jeong I, Oh M, Kim JH, Cho JH, Choi JH, Yoo HW

Cushing disease is caused by excessive adrenocorticotropic hormone (ACTH) production by the pituitary adenoma. Transsphenoidal surgery is its first-line treatment. The incidence of Cushing disease in children and adolescents is...
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Comparisons between Macroadenomas and Microadenomas in Cushing's Disease: Characteristics of Hormone Secretion and Clinical Outcomes

Hwang YC, Chung JH, Min YK, Lee MS, Lee MK, Kim KW

It has been suggested that the patients with Cushing's disease secondary to pituitary macroadenomas (>10 mm) have higher basal adrenocorticotropic hormone (ACTH) levels, which are less suppressible on high-dose dexamethasone...
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Proteomic and Transcriptomic Analysis of Interleukin-1beta Treated Airway Epithelial Cells

Kim CH, Baek SJ, Kim PH, Yoon JH

  • KMID: 2037112
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Feb;48(2):158-171.
BACKGROUND AND OBJECTIVES: Mucin hypersecretion is one of the main symptoms of inflammatory diseases in the respiratory tract. The authors previously reported that pleiotypic pro-inflammatory cytokine, interleukin (IL)-1beta, plays significant...
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A Case of Atypical McCune-Albright Syndrome Associated with Hyperthyroidism and Hypersecretion of Growth Hormone

You MB, Kang KH, Lee BS, Chae EH, Kim MC, Jung JI, Park SH, Lee HJ, Jung ST

  • KMID: 2200390
  • J Korean Soc Endocrinol.
  • 2003 Aug;18(4):426-432.
McCune-Albright syndrome is characterized by polyostotic fibrous dysplasia, Caf -au-lait pigmentation and precocious puberty or other endocrinopathy. It can be caused by substitution of His, Cys or Gly for Arg...
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The Role of Neutrophils and Epidermal Growth Factor Receptors in Lipopolysaccharide-Induced Mucus Hypersecretion

Bak SM, Park SY, Hur GY, Lee SH, Kim JH, Lee SY, Shin C, Shim JJ, In KH, Kang KH, Yoo SH

BACKGROUND: Goblet cell hyperplasia is a critical pathological feature in hypersecretory diseases of the airways. A bacterial infection of the lung is also known to induce inflammatory responses, which can...
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One Case of Mucin Hypersecreting Papillary Adenocarcinoma of the Left Intrahepatic Duct

Joo DH, Yoo YO, Song SH, Lee HI, Park KH, Kim YI, Kim HG, Park JB

  • KMID: 2083087
  • Korean J Hepatobiliary Pancreat Surg.
  • 1997 Aug;1(2):179-184.
A patient with mucin hypersecreting papillary adenocarcinoma of intrahepatic bile duct had jaundice and symptoms of cholangitis. Radiologic evaluations-ultrasonography and computerized tomographyrevealed passage disturbance of bile at the level of...
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A Case of Gonadotropin-Producing Pituitary Adenoma

Lee SD, Ha YS, Park CO, Kim Y, Chae KB, Kim JM

  • KMID: 2067968
  • J Korean Neurosurg Soc.
  • 1993 Jun;22(6):770-778.
A 58-year-old male with a pituitary adenoma was investigated and demonstrated to have hypersecretion of both gonadotropins in the basal state. Presenting symptoms included visual disturbance, headache, loss of libido,...
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