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Luteolin inhibits H2O2 -induced cellular senescence via modulation of SIRT1 and p53

Zhu RZ, Li BS, Gao SS, Seo JH, Choi BM

Luteolin, a sort of flavonoid, has been reported to be involved in neuroprotective function via suppression of neuroinflammation. In this study, we investigated the protective effect of luteolin against oxidative...
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Effects of Citrus limon Extract on Oxidative Stress-Induced Nitric Oxide Generation and Bovine Teeth Bleaching

Jeong SJ

Background: We aimed to investigate the effect of Citrous limon extract (CLE) on oxidative stress-induced cytotoxicity and nitric oxide (NO) generation and the tooth bleaching effect of CLE as a...
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Alpha-lipoic acid protects human dopaminergic neuronal cells against hydrogen peroxide-induced cell injury by inhibiting autophagy and apoptosis

Kang KR, Kim JS, Kim TH, Seo JY, Lim H, Park JH, Yang KY, Yu SK, Kim HJ, Kim CS, Chun HS, Lee DS, Park JC, Kim DK

Alpha-lipoic acid (ALA) is a naturally occurring antioxidant and has been previously used to treat diabetes and cardiovascular disease. However, the autophagy effects of ALA against oxidative stress-induced dopaminergic neuronal...
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Hydrogen peroxide as an auxiliary treatment for COVID-19 in Brazil: a randomized double-blind clinical trial

Domênico MBD, Collares K, Santos RBd, Lenz U, Antunes VP, Godinho VW, Cesca H, Ponciano THJ, Corazza PH

OBJECTIVES: This study evaluated the effectiveness of hydrogen peroxide (H2O2) as mouthwash and nasal spray on symptom relief in coronavirus disease 2019 (COVID-19) patients. METHODS: Patients positive for severe acute respiratory...
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Effectiveness of hydrogen peroxide as auxiliary treatment for hospitalized COVID-19 patients in Brazil: preliminary results of a randomized double-blind clinical trial

Di Domênico MB, Cesca H, Ponciano THJ, dos Santos RB, Lenz U, Antunes VP, Godinho VW, Collares K, Corazza PH

OBJECTIVES: To evaluate the effectiveness of hydrogen peroxide (H2O2) in the form of mouthwash and nasal spray as an auxiliary treatment for coronavirus disease 2019 (COVID-19). METHODS: Forty hospitalized patients who...
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Residual Concentration of Hydrogen Peroxide after Nocospray® Dispersion in Negative Pressure Isolation Room

Yim JY, Kim NY, Lee Y, Kim GE, Jung DU, Kim EJ, Heo JY, Choi YH, Lim KJ

Non-touch technology using UV vapor or hydrogen peroxide vapor has been been introduced for environmental decontamination in hospitals. Hydrogen peroxide is a hazardous substance; therefore, any exposure should be to...
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A case of hydrogen peroxide-induced proctocolitis in a child

Choi SY

Hydrogen peroxide is a strong oxidizing agent widely available as disinfectants. It can be harmful if it enters into the bowels. Within moments after gastrointestinal exposure, the colon becomes distended...
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Influence of pain-relieving therapies on inflammation and the expression of proinflammatory neuropeptides after dental bleaching treatment

Silva LMAVd, Cintra LTA, Gallinari MdO, Benetti F, Rahal V, Ervolino E, Alcântara Sd, Briso ALF

Objectives: To minimize the tooth sensitivity caused by in-office bleaching, many dentists use non-steroidal anti-inflammatory drugs and topical desensitizing gels containing potassium nitrate and sodium fluoride. This study aimed to...
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Oxidative Stress Modulates the Expression Pattern of Peroxiredoxin-6 in Peripheral Blood Mononuclear Cells of Asthmatic Patients and Bronchial Epithelial Cells

Shim HJ, Park SY, Kwon HS, Song WJ, Kim TB, Moon KA, Choi JP, Kim SJ, Cho YS

PURPOSE: Reduction-oxidation reaction homeostasis is vital for regulating inflammatory conditions and its dysregulation may affect the pathogenesis of chronic airway inflammatory diseases such as asthma. Peroxiredoxin-6, an important intracellular anti-oxidant...
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Surface Damage and Bleaching Effect according to the Application Type of Home Tooth Bleaching Applicants

Tak NY, Lim DS, Lim HJ, Jung IH

Background: In this study, the bleaching effect and surface damage of two types of over-the-counter home tooth bleaching agents were explored using an in vitro study of bleaching agents applied...
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The biofilm removal effect of MnOâ‚‚-diatom microbubbler from the dental prosthetic surfaces: In vitro study

Lee EH, Seo Y, Kwon HB, Yim YJ, Kong H, Kim MJ

PURPOSE: The aim of this study is to evaluate the effectiveness of MnOâ‚‚-diatom microbubbler (DM) on the surface of prosthetic materials as a mouthwash by comparing the biofilm removal effect...
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Cyclosporin A aggravates hydrogen peroxide-induced cell death in kidney proximal tubule epithelial cells

Moon D, Kim J

Cyclosporin A (CsA) does not only exert a toxic effect on kidney parenchymal cells, but also protects them against necrotic cell death by inhibiting opening of mitochondrial permeability transition pore....
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Protective effect of Cordyceps militaris against hydrogen peroxide-induced oxidative stress in vitro

He MT, Lee AY, Park CH, Cho EJ

BACKGROUND/OBJECTIVES: Excessive production of reactive oxygen species (ROS) such as hydroxyl (·OH), nitric oxide (NO), and hydrogen peroxide (H2O2) is reported to induce oxidative stress. ROS generated by oxidative stress...
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A simple and effective method for addition silicone impression disinfection

Azevedo MJ, Correia I, Portela A, Sampaio-Maia B

PURPOSE: Although dental impression disinfection is determinant to reduce the cross-infection risk, some studies have shown that, in real practice, the disinfection procedures vary considerably. Thus, the aim of this...
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Tooth whitening effects of manicure-type hydrogen peroxide tooth whitening gel

Kim YG, Park JH, Cho JW

OBJECTIVES: To examine the tooth whitening effects of a 3% hydrogen peroxide gel. METHODS: Twenty participants were given experimental tooth whitening gels containing 3% hydrogen peroxide, and another 20 participants, who...
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Efficacy of a self - applied paint - on whitening gel combined with wrap

Kim SY, Ahn JH, Kim JY, Kim JW, Park SH, Cho KM

PURPOSE: The aim of this clinical study was to evaluate the efficacy and safety of a self - applied paint - on whitening gel combined with wrap to increase the...
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Protective effects of perilla oil and alpha linolenic acid on SH-SY5Y neuronal cell death induced by hydrogen peroxide

Lee AY, Choi JM, Lee MH, Lee J, Lee S, Cho EJ

BACKGROUND/OBJECTIVE: Oxidative stress plays a key role in neuronal cell damage, which is associated with neurodegenerative disease. The aim of present study was to investigate the neuroprotective effects of perilla...
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Hydrogen peroxide inhibits Ca²⁺ efflux through plasma membrane Ca²⁺-ATPase in mouse parotid acinar cells

Kim MJ, Choi KJ, Yoon MN, Oh SH, Kim DK, Kim SH, Park HS

Intracellular Ca²⁺ mobilization is closely linked with the initiation of salivary secretion in parotid acinar cells. Reactive oxygen species (ROS) are known to be related to a variety of oxidative...
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Chemical Colitis Caused by Hydrogen Peroxide Enema in a Child : A Case Report and Literature Review

Lee JS, Yoo JK

A 2-year-old girl, previously healthy, was brought to our emergency department due to abdominal pain (cramping), following recurrent hematochezia after an accidental hydrogen peroxide enema (35%, 5 mL) by her...
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A Case of Delayed Tracheo-esophageal Fistula Complicating Acute Intoxication of Hydrogen Peroxide

Cho HY, Koh CY

Hydrogen peroxide is a commonly used oxidizing agent. If injected, it may result in morbidity via direct caustic injury, oxygen gas formation, and lipid peroxidation. We report a 40-year-old male...
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