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Hydrogen Peroxide as an Effective Disinfectant for Pasteurella multocida

Jung IS, Kim HJ, Jung WY, Kim CW

Pasteurella multocida (P. multocida) infections vary widely, from local infections resulting from animal bites and scratches to general infections. As of yet, no vaccine against P. multocida has been developed,...
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Hydrogen Peroxide Upregulates TNF-Related Apoptosis-Inducing Ligand (TRAIL) Expression in Human Astroglial Cells, and Augments Apoptosis of T Cells

Kwon D, Choi IH

The brain is particularly vulnerable to oxygen free radicals, and these radicals have been implicated in the pathology of several neurological disorders. In this study, the modulation of TNF-related apoptosis-inducing...
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Hydrogen Peroxide-Induced Cell Death in a Human Retinal Pigment Epithelial Cell Line, ARPE-19

Kim MH, Chung J, Yang JW, Chung SM, Kwag NH, Yoo JS

The loss of retinal pigment epithelium (RPE) with aging is related to age-related macular degeneration (AMD). This study was conducted to investigate the mechanism of hydrogen peroxide (H2O2) induced cell...
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Effect of serum and hydrogen peroxide on the Ca2+/calmodulin-dependent phosphorylation of eukaryotic elongation factor 2(eEF-2) in Chinese hamster ovary cells

Kang KR, Lee SY

  • KMID: 1457530
  • Exp Mol Med.
  • 2001 Dec;33(4):198-204.
Eukaryotic elongation factor eEF-2 mediates regulatory steps important for the overall regulation of mRNA translation in mammalian cells and is activated by variety of cellular conditions and factors. In this...
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Human Papilloma Virus Type 16 E7 Genes Protect Astrocytes against Apoptotic and Necrotic Death Induced by Hydrogen Peroxide

Lee WT, Lee JE, Lee SH, Jang HS, Giffard RG, Park KA

Hydrogen peroxide is considered to be a dose- and time-dependent mediator in apoptotic and necrotic death. In this study, we examined the signaling of the E6 and E7 proteins with...
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Centrosome amplification and multinuclear phenotypes are Induced by hydrogen peroxide

Chae S, Yun C, Um H, Lee JH, Cho H

  • KMID: 1089458
  • Exp Mol Med.
  • 2005 Oct;37(5):482-487.
Multinucleated cells resulted from mitosis defect have been noted in pathophysiological states of the cells such as inflammation, senescence and cancer. Since oxidative stress has been known to correlate with...
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Transient exposure to hydrogen peroxide inhibits the ubiquitination of phosphorylated IkappaBalpha in TNFalpha-stimulated HEK293 cells

Lee Y, Choi J, Ha KH, Jue DM

  • KMID: 1387362
  • Exp Mol Med.
  • 2012 Aug;44(8):513-520.
During ischemia-reperfusion injury, brief pre-exposure to oxidative stress renders organs resistant to subsequent severe damage. NF-kappaB is a transcription factor that is involved in reperfusion-induced inflammatory and immune responses. The...
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Proteomic analysis of the cellular proteins induced by adaptive concentrations of hydrogen peroxide in human U937 cells

Seong JK, Kim DK, Choi KH, Oh SH, Kim KS, Lee SS, Um HD

  • KMID: 755210
  • Exp Mol Med.
  • 2002 Nov;34(5):374-378.
When cells are first exposed to low levels of oxidative stress, they develop a resistance to a subsequent challenge of the same stress, even at higher levels. Although some protein(s)...
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Slug suppression induces apoptosis via Puma transactivation in rheumatoid arthritis fibroblast-like synoviocytes treated with hydrogen peroxide

Cha HS, Bae EK, Ahn JK, Lee J, Ahn KS, Koh EM

Inadequate apoptosis contributes to synovial hyperplasia in rheumatoid arthritis (RA). Recent study shows that low expression of Puma might be partially responsible for the decreased apoptosis of fibroblast-like synoviocytes (FLS)....
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Effect of dihydrotestosterone on mouse embryonic stem cells exposed to H(2)O(2)-induced oxidative stress

Lee MN, Lee SH, Lee MY, Kim YH, Park JH, Ryu JM, Yun SP, Lee YJ, Kim MO, Park K, Han HJ

Oxidative stresses induced by reactive oxygen species (ROS) have been shown to be involved in several physiological and pathophysiological processes, such as cell proliferation and differentiation. Steroid hormones can protect...
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H2O2 Enhances Ca2+ Release from Osteoblast Internal Stores

Nam SH, Jung SY, Yoo CM, Ahn EH, Suh CK

The physiological activity of osteoblasts is known to be closely related to increased intracellular Ca2+ activity ([Ca2+]i) in osteoblasts. The cellular regulation of [Ca2+]i in osteoblasts is mediated by Ca2+...
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