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Studies on expression of DNA topoisomerases genes and protooncogene c-Myc during hepatocarcinogenesis

Hwang BD, Won SH, Kwon KR, Kim KY, Kang DY, Kwak ST, Lim K

  • KMID: 1694362
  • J Korean Cancer Assoc.
  • 1993 Oct;25(5):636-650.
No abstract available.
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Specialized Functions and Hormonal Regulation of Sertoli Cell

Lim K, Park C, Yun KA, Yun EJ, Park JI, Park SK, Hwang BD

  • KMID: 2331168
  • J Korean Soc Endocrinol.
  • 2003 Apr;18(2):120-136.
No abstract available.
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The Gene Expression of Dynorphin, Enkephalin, c-Fos in the Neuropathic Rat

Han NH, Lee WH, Hwang WJ, Yoon SH, Shin YS, Son SC, Kim HJ, Choi SJ, Lim K, Hwang BD

BACKGROUND: We studied the time course of gene expression of dynorphin, enkephalin, c-fos, and the changes of allodynia, and the effect of chemical sympathectomy on the gene expression and allodynia...
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Association of castration-dependent early induction of c-myc expression with a cell proliferation of the ventral prostate gland in rat

Lim K, Park C, Kim YK, Yun KA, Son MY, Lee YC, Park JI, Lee JH, Sul CK, Lee CS, Park SK, Hwang BD

  • KMID: 755102
  • Exp Mol Med.
  • 2000 Dec;32(4):216-221.
The protooncogene c-myc is known to be associated with both cell proliferation and apoptosis. The possible cellular affects of castration on the ventral prostate gland of rat as...
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Smoking Status and the Related Factors in the Rural Elderly

Beak DH, Hwang BD, Moon HJ, Yoon HJ, Back YD, Lee SK

  • KMID: 2285662
  • J Agric Med Community Health.
  • 2008 Sep;33(2):243-254.
OBJECTIVE: The purpose of this study was to examine smoking status and the relates factors in the rural elderly. METHODS: This study was conducted with 2,421 elderly people(male 1,273 and female...
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Study of Pro-inflammatory Cytokines in Endotoxin Induced Uveitis

Park JM, Hwang BD

  • KMID: 2336744
  • J Korean Ophthalmol Soc.
  • 1999 Jan;40(1):110-120.
Cytokines are produced during the effector phases of natural and specific immunity and serve to mediate and regulate immune and inflammatory responses. In natural immunity,endotoxin directly stimulates mononuclear phagocytes to...
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Influence Factors on Health and Medical of Retirees Expense to Public Pension Recipients

Choi R, Hwang BD

BACKGROUND: This study aims to identify the monthly average medical expenses of public pension recipients, and analyze the determinants of total health and medical expenses and Western and Oriental medicine...
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Role of Cell Surface Mucin on Invasion and Metastasis of HM7 Colon Cancer Cells

Yoon WH, Park HD, Lim K, Hwang BD

  • KMID: 2175468
  • J Korean Cancer Assoc.
  • 1997 Apr;29(2):309-320.
PURPOSE: Mucinous colorectal cancers have a poorer prognosis than which colorectal cancer produce low amount of mucin, but the exact mechanism is not well understood. The present study was undertaken...
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The Effects of NMDA Antagonists and Sympathectomy on the c-Fos mRNA Expression in the Neuropathic Rat

Kim JL, Han KC, Kim SS, Hur DS, Lim K, Hwang BD, Lee WH

BACKGROUND: Neuropathic pain produced by nerve injury has the characteristics of enhanced pain responses - allodynia. To understand the pathophysiology of the neuropathic pain, We evaluated the effect of NMDA...
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Epidermal Growth Factor Dependent Expression of Plasminogen Activator and Plasminogen Activator Inhibitor in Rat Hepatocytes in Primary Culture

Yoon WH, Choi JH, Jung YJ, Lee BH, Kim TD, Song IS, Bae JS, Lim K, Hwang BD

  • KMID: 2095927
  • J Korean Surg Soc.
  • 2001 Sep;61(3):237-246.
PURPOSE: In order to clarify the the role of epidermal growth factor (EGF) in the regulation of plasminogen activator (PA) and plasminogen activator inhibitor (PAI) during liver regeneration, we investigated...
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Activation of epidermal growth factor receptor is responsible for pervanadate-induced phospholipase D activation

Kim YR, Cha HY, Lim K, Hwang BD, Hoe KL, Namgung U, Park SK

  • KMID: 1097260
  • Exp Mol Med.
  • 2003 Apr;35(2):118-124.
Pervanadate, a complex of vanadate and H2O2, has an insulin mimetic effect, and acts as an inhibitor of protein tyrosine phosphatase. Pervanadate-induced phospholipase D (PLD) activation is known to be...
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Transcriptional Regulation of the Estrogen Receptor alpha Gene by Testosterone in Cultures of Primary Rat Sertoli Cells

Yang SK, Yoon KA, Yun EJ, Song KS, Kim JS, Kim YR, Park JI, Park SK, Hwang BD, Lim K

BACKGROUND: We wanted to identify the presence of the estrogen receptor (ER) alpha in Sertoli cells and gain insight on the regulation of the ER alpha gene expression by testosterone...
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Mechanism of Azaline B-induced Apoptosis of Ventral Prostate in Rat

Park C, Nam SI, Yun EJ, Park JI, Lee JH, Park SK, Hwang BD, Lim K

  • KMID: 2293576
  • Korean J Urol.
  • 2003 Nov;44(11):1157-1166.
PURPOSE: Androgen deprivation triggers a sequence of events that activates apoptotic cell death of the androgen-dependent epithelial cells within the rat ventral prostate, ultimately resulting in the involution of the...
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Transcriptional Regulation of H2B Histone Gene Expression by Nocodazole in HL-60 Cells

Lim K, Hong YG, Lee MS, Son MY, Yun KA, Park JI, Yoon WH, Park SK, Hwang BD

  • KMID: 2175113
  • J Korean Cancer Assoc.
  • 2000 Apr;32(2):407-416.
PURPOSE: Nocodazole, a microtubule disrupting reagent, is known to arrest cells in the M phase, To gain insight on the regulatory mechanism of H2B histone gene expression by nocodazole in HL-60 cell,...
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Mechanism of Castration-induced Apoptosis of Ventral Prostate in Rat

Park C, Park JI, Yun EJ, Song KS, Kim JS, Kim YR, Lee SD, Park SK, Hwang BD, Lim K

BACKGROUNDS: Castration-induced androgen deprivation triggers a sequence of events, which activates apoptotic cell death of the androgen-dependent epithelial cells within the rat ventral prostate. To investigate the mechanism of castration-dependent...
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Transcriptional REpression of Vimentin Gene During All-TTrans Retinoic Acid-Induced Differentiation of HL-60 Cells

Lim K, Kwon DW, Kim SM, Yoon KA, Son MY, Lee MS, Park JI, Yoon WH, Hwang BD

  • KMID: 1944218
  • J Korean Soc Endocrinol.
  • 1998 Dec;13(4):601-611.
BACKGROUND: Vimentin is the major intermediate-size filament in the cytoplasm of cells from mesenchymal origin. The HL-60 cell is a unique human leukemic cell line capable of terminal differentiation with...
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Role of ATF on Transcriptional Regulation of DNA Topoisomerase II a Gene in HL - 60 Arrested to G2 / M and M Phase

Lim K, Son MY, Choi BI, Yun KA, Zheng M, Kang TW, Lee YC, Park JI, Yoon WH, Hwang BD

  • KMID: 2175140
  • J Korean Cancer Assoc.
  • 1999 Dec;31(6):1279-1287.
PURPOSE: To gain insight on transcriptional repression of Topo II a in HL-60 cells arrested to G2/M and M phase, the levels of Topo IIa mRNA and the binding activity...
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Mechanism of Azaline B-induced Apoptosis in Rat Testis

Park C, Yun EJ, Song KS, Kim YR, Kim JS, Lee SD, Park JI, Lee JH, Park SK, Hwang BD, Lim K

  • KMID: 2293996
  • Korean J Urol.
  • 2005 Jul;46(7):750-760.
PURPOSE: To identify the mechanism of azaline B-dependent apoptosis, the regulation of Fas and FasL genes has been investigated. MATERIALS AND METHODS: Azaline B was subcutaneously injected into Sprague-Dawley rats. The...
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Role of AP-1 Transcriptional Regulation of Vimentin Gene during 12-O-Tetradecanoylphorbol-13-Acetate Differentiation of HL-60 Cells

Lim K, Kim JH, Kweon DW, Kim SM, Lee MS, Yun KA, Son MY, Park JI, Yoon WH, Hwang BD

  • KMID: 2175342
  • J Korean Cancer Assoc.
  • 1998 Oct;30(5):997-1004.
PURPOSE: To gain insight on the role of AP-1 in transcriptional regulation of vimentin gene during differentiation of HL-60 cells by 12-0-tetradecanoylphorbol-13-acetate (TPA), the levels of vimentin mRNA and AP-1...
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