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The role of different viral biomarkers on the management of chronic hepatitis B

Mak LY, Hui RWH, Fung J, Seto WK, Yuen MF

Chronic hepatitis B infection is a major public health challenge. With the advancement in technology, various components of the viral cycle can now be measured in the blood to assess...
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RNA interference as a novel treatment strategy for chronic hepatitis B infection

Hui RWH, Mak LY, Seto WK, Yuen MF

Chronic hepatitis B (CHB) is a major cause of liver-related morbidity and mortality. Functional cure of CHB, defined as sustainable hepatitis B surface antigen (HBsAg) seroclearance, is associated with improved...
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Clinical practice guidelines and real-life practice on hepatocellular carcinoma: the Hong Kong perspective

Hui RWH, Mak LY, Cheung TT, Lee VHF, Seto WK, Yuen MF

Hepatocellular carcinoma (HCC) is a major public health burden in Hong Kong, and chronic hepatitis B is the most common HCC etiology in our region. With the high case load,...
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Effect of moderate-to-severe hepatic steatosis on neutralising antibody response among BNT162b2 and CoronaVac recipients

Cheung KS, Lam LK, Hui RWH, Mao X, Zhang RR, Chan KH, Hung IF, Seto WK, Yuen MF

Background/Aims: Studies of hepatic steatosis (HS) effect on COVID-19 vaccine immunogenicity are lacking. We aimed to compare immunogenicity of BNT162b2 and CoronaVac among moderate/severe HS and control subjects. Methods: Two hundred...
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