- Optimizing off-treatment outcome predictions: The potential of time-varying HBcrAg and the need for more research
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Tsai YN, Wu JL, Hsu YC
- KMID: 2554436
- Clin Mol Hepatol.
- 2024 Apr;30(2):276-278.
- doi: 10.3350/cmh.2024.0220
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- Harnessing hepatitis B core-related antigen measurement to optimize posttreatment monitoring
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Tsai YN, Wu JL, Hsu YC
- KMID: 2554442
- Clin Mol Hepatol.
- 2024 Apr;30(2):293-296.
- doi: 10.3350/cmh.2024.0101
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- Use of glecaprevir/pibrentasvir in patients with chronic hepatitis C virus infection and severe renal impairment
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Yap DYH, Liu KSH, Hsu YC, Wong GLH, Tsai MC, Chen CH, Hsu CS, Hui YT, Li MKK, Liu CH, Kan YM, Yu ML, Yuen MF
- KMID: 2507974
- Clin Mol Hepatol.
- 2020 Oct;26(4):554-561.
- doi: 10.3350/cmh.2020.0058
Background/Aims: Data on treatment efficacy and safety of glecaprevir/pibrentasvir (GLE/PIB) for chronic hepatitis C virus (HCV) infection in Asian patients with severe renal impairment are limited. This study aimed to... -
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- Taking a Closer Look at Bus Driver Emotional Exhaustion and Well-Being: Evidence from Taiwanese Urban Bus Drivers
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Chen CF, Hsu YC
- KMID: 2506950
- Saf Health Work.
- 2020 Sep;11(3):353-360.
- doi: 10.1016/j.shaw.2020.06.002
Background: Urban bus drivers work under conditions that are among the most demanding, stressful, and unhealthy with higher rates of mortality and morbidity as well as absenteeism and turnover. Methods: Drawing... -
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- Comparison of the Efficacy of Two Microsphere Embolic Agents for Transcatheter Arterial Chemoembolization in Hepatocellular Carcinoma Patients
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Lee SH, Lin CY, Hsu YC, Liu YS, Chuang MT, Ou MC
- KMID: 2501198
- Cancer Res Treat.
- 2020 Jan;52(1):24-30.
- doi: 10.4143/crt.2019.018
Purpose Transarterial chemoembolization (TACE) delivers cytotoxic drugs intra-arterially and induces ischemic necrosis by arterial embolization. Embolization is achieved using a variety of agents that differ widely in particle size and range,... -
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- Safety considerations for withdrawal of nucleos(t)ide analogues in patients with chronic hepatitis B: First, do no harm
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Hsu YC, Tseng CH, Kao JH
- KMID: 2546375
- Clin Mol Hepatol.
- 2023 Oct;29(4):869-890.
- doi: 10.3350/cmh.2022.0420
Nucleos(t)ide analogues (NA) are widely used to treat hepatitis B virus (HBV) infection, but they cannot eradicate the virus and treatment duration can be lifelong if the endpoint is set... -
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- Strategies to Improve Neurological Safety in Full-Endoscopic Lumbar Fusion Surgery: A Comprehensive Review
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Hsu YC, Liu YF, Chang CJ, Hsiao YM, Huang YH, Liu KC, Chen CM, Lin CL
- KMID: 2562242
- J Minim Invasive Spine Surg Tech.
- 2024 Jan;9(Suppl 1):S3-S13.
- doi: 10.21182/jmisst.2023.01130
Full-endoscopic spinal fusion surgery has emerged as a crucial approach for managing lumbar degenerative spinal disease. A significant concern in endoscopic spinal fusion relates to the vulnerability of neural structures,... -
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- Innovative Nerve Root Protection in Full-Endoscopic Facet-Resecting Lumbar Interbody Fusion: Controlled Cage Glider Rotation Using the GUARD (Glider Used As a Rotary Device) Technique
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Hsu YC, Chuang HC, Chang WL, Liu YF, Chang CJ, Hsiao YM, Huang YH, Liu KC, Chen CM, Kim HS, Lin CL
- KMID: 2563111
- Neurospine.
- 2024 Dec;21(4):1141-1148.
- doi: 10.14245/ns.2449126.563
This video presents a case of L4–5 unstable spondylolisthesis treated with full-endoscopic transforaminal lumbar interbody fusion (Endo-TLIF), emphasizing the GUARD (Glider Used as a Rotary Device) technique for nerve root... -
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- Reducing Postoperative Neurological Complications in Uniportal Full-Endoscopic Lumbar Interbody Fusion: Efficacy of the GUARD Technique Combined With Delayed Ligamentum Flavectomy
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Chuang HC, Hsu YC, Liu YF, Chang CJ, Hsiao YM, Huang YH, Liu KC, Chen CM, Kim HS, Lin CL
- KMID: 2563119
- Neurospine.
- 2024 Dec;21(4):1199-1209.
- doi: 10.14245/ns.2448656.328
Objective: Uniportal full-endoscopic transforaminal lumbar interbody fusion (FE-TLIF) carries a unique risk of nerve traction and abrasion injury during cage insertion. This study aims to evaluate the clinical efficacy of... -
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- Hepatitis B core-related antigen dynamics and risk of subsequent clinical relapses after nucleos(t)ide analog cessation
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Tsai YN, Wu JL, Tseng CH, Chen TH, Wu YL, Chen CC, Fang YJ, Yang TH, Nguyen MH, Lin JT, Hsu YC
- KMID: 2549386
- Clin Mol Hepatol.
- 2024 Jan;30(1):98-108.
- doi: 10.3350/cmh.2023.0194
Background/Aims: Finite nucleos(t)ide analog (NA) therapy has been proposed as an alternative treatment strategy for chronic hepatitis B (CHB), but biomarkers for post-treatment monitoring are limited. We investigated whether measuring... -
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- Phase 1 trial of the safety, pharmacokinetics, and antiviral activity of EDP-514 in untreated viremic chronic hepatitis B patients
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Yuen MF, Chuang WL, Peng CY, Jeng WJ, Su WW, Chang TT, Chen CY, Hsu YC, De La Rosa G, Ahmad A, Luo E, Conery AL
- KMID: 2557390
- Clin Mol Hepatol.
- 2024 Jul;30(3):375-387.
- doi: 10.3350/cmh.2023.0535
Background/Aims: Oral EDP-514 is a potent core protein inhibitor of hepatitis B virus (HBV) replication, which produced a >4-log viral load reduction in HBV-infected chimeric mice with human liver cells.... -
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- Antiviral therapy for chronic hepatitis B with mildly elevated aminotransferase: A rollover study from the TORCH-B trial
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Hsu YC, Chen CY, Tseng CH, Chen CC, Lee TY, Bair MJ, Chen JJ, Huang YT, Chang IW, Chang CY, Wu CY, Wu MS, Mo LR, Lin JT
- KMID: 2563421
- Clin Mol Hepatol.
- 2025 Jan;31(1):213-226.
- doi: 10.3350/cmh.2024.0640
Background/Aims: Treatment indications for patients with chronic hepatitis B (CHB) remain contentious, particularly for patients with mild alanine aminotransferase (ALT) elevation. We aimed to evaluate treatment effects in this patient... -
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