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Generation of Hepatic Progenitor Cells from the Primary Hepatocytes of Nonhuman Primates Using Small Molecules

Hong DH, Lee C, Kim Y, Bum S, Han SC, Kim SJ, Yang HM, Choi D, Jeong J, Ryu K

BACKGROUND: Since primates have more biological similarities to humans than do other animals, they are a valuable resource in various field of research, including biomedicine, regenerative medicine, and drug discovery....
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Non-viral ex vivo therapeutic strategy in chemically derived hepatic progenitor with adenine base editor and prime editor

Kim Y, Yoon S, Kim MH, Hong DH, Kim T, Jeong J, Choi D

Background: The adenine base editor (ABE) and prime editing converts nucleotide in living cells without double strand DNA breaks. Chemically derived stem/progenitor cells are attracting attention as the most applicable...
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Expandable liver organoids generated from human chemically derived hepatic progenitor enable alcoholic liver modeling

Kim Y, Yoon S, Kim MH, Hong DH, Kim Th, Jeong Jm, Choi D

Background: Liver organoids, an attracting source for studying cell to cell interaction, drug screening, and disease modeling in three-dimension systems were demonstrated to be developed from EpCAM+ cells. Our group...
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Liver tissueoid composed of electrospun multiscale fiber enhance hepatic differentiation and therapeutic function of chemical derived hepatic stem cells

Kim Y, Yoon S, Hong DH, Kim MH, Kim T, Jeong J, Choi D

Background: Artificial tissueoid has tissue-like properties that consist of multicellular component and three-dimension microenvironments. This model recapitulated the in situ environment interactions by providing structure, physiology, and arrangement of individual...
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Use of a ring retractor to facilitate specimen removal in laparoscopic surgery

Hong DH, Kim M, Kim K, Suh DH, No JH, Kim YB

Objective To introduce a new surgical technique for specimen removal during laparoscopic surgery. Methods The surgical technique was described, pictured, and recorded. The surgery was performed in a tertiary hospital. Results During...
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Levels of Clinical Practice Stress and Coping Strategies according to Nursing Students' Personality/Behavior Types

Jang S, Kim SJ, Kim YJ, Suh IY, Song C, Oh HK, Lee IJ, Lee JY, Lee JE, Hong DH, Kim J

PURPOSE: This study was performed to identify levels of clinical practice stress and coping strategies according to the personality/behavior types of nursing students. METHODS: The subjects of this study were 143...
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Safety of cesarean delivery through placental incision in patients with anterior placenta previa

Hong DH, Kim E, Kyeong KS, Hong SH, Jeong EH

OBJECTIVE: To demonstrate the safety of fetal delivery through placental incision in a placenta previa pregnancy. METHODS: We examined the medical records of 80 women with singleton pregnancy diagnosed with placenta...
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A Case Report of Heterokaryotypic Monochorionic Twin Pregnancy with Discordant for Turner Syndrome

Jang JH, Kyeong KS, Hong DH, Hong SH, Ji I, Jeong EH

Monochorionic twins with discordant karyotypes are rare and mostly caused by post-zygotic mitotic nondisjunction. A 32 year old nulliparous woman at 11 weeks of gestation with spontaneous twin pregnancy was...
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Effect of repeated Paecilomyces japonica treatment on rats

Kim YB, Hong DH, Cho ES, Im W, Kim IH, Son HY

  • KMID: 1700788
  • Korean J Vet Res.
  • 2014 Mar;54(1):31-38.
Cordyceps is a fungus used as a traditional medicine in China, Japan, and Korea. Paecilomyces (P.) japonica is a new cordyceps that was recently cultivated on silkworm pupae in Korea....
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Recovery of lingual nerve injury: retrospective observational study

Hong DH, Lim HK, Kim SM, Kim MJ, Lee JH

  • KMID: 2328608
  • J Korean Assoc Oral Maxillofac Surg.
  • 2011 Oct;37(5):355-364.
INTRODUCTION: This study evaluated nerve recovery through retrospective study of patients with lingual nerve damage. PATIENTS AND METHODS: The patients who visited Seoul National University Dental Hospital for an injury to...
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A Carbohydrate Fraction, AIP1, from Artemisia Iwayomogi Reduces the Action Potential Duration by Activation of Rapidly Activating Delayed Rectifier K+ Channels in Rabbit Ventricular Myocytes

Park WS, Son YK, Ko EA, Choi SW, Kim N, Choi TH, Youn HJ, Jo SH, Hong DH, Han J

We investigated the effects of a hot-water extract of Artemisia iwayomogi, a plant belonging to family Compositae, on cardiac ventricular delayed rectifier K+ current (I(K)) using the patch clamp technique....
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The Role of General Surgeon in Gynecologic Oncology Surgery

Choi PW, Yu CS, Jung SH, Kim DD, Hong DH, Kim HC, Kim JC

  • KMID: 2211138
  • J Korean Surg Soc.
  • 2008 Apr;74(4):237-242.
PURPOSE: Resection of the bowel or solid organs may be required for pelvic tumor surgery. The present study was performed to assess combined surgical procedures and determine the role of...
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Desmoid Tumor in Familial Adenomatous Polyposis (FAP)

Kim DD, Yu CS, Hong DH, Jung SH, Choi PW, Park IJ, Kim HC, Kim JC

PURPOSE: This research was conducted to assess the incidence, clinical characteristics, and treatment outcomes for desmoid tumors in patients with familial adenomatous polyposis (FAP). METHODS: At Medical Center, we recruited...
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Postoperative Complications and Recurrence in Patients with Crohn's Disease

Hong DH, Yu CS, Kim DD, Jung SH, Choi PH, Park IJ, Kim HC, Kim JC

PURPOSE: This study was performed to assess postoperative complications and recurrence rates and to elucidate the risk factors in Crohn's disease (CD). METHODS: A retrospective review was undertaken for patients...
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Is a Short Distal Resection Margin of Less than One Centimeter in a Sphincter-saving Resection for Rectal Cancer Oncologically Safe?

Cho MJ, Yu CS, Park IJ, Jeong SH, Chae PH, Hong DH, Kim DD, Kim HC, Kim JC

PURPOSE: Sphincter preservation is one of the main goals in the treatment of rectal cancer. The aim of this study was to evaluate the oncologic safety of a sphincter-saving resection...
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Distant Metastasis Identified Immediately after Preoperative Chemoradiotherapy for Locally Advanced Rectal Cancer

Park IJ, Kim HC, Yu CS, Choi PH, Jung SH, Hong DH, Kim DD, Ryu MH, Chang HM, Kim JH, Kim JC

  • KMID: 2334398
  • J Korean Soc Coloproctol.
  • 2007 Oct;23(5):327-332.
PURPOSE: This study was designed to analyze the clinical characteristics of patients with immediate distant metastasis after preoperative chemoradiotherapy for locally advanced rectal cancer and to help select patients for...
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The Relationship between Economic Status and Adolescent Obesity in Incheon, Korea

Kim JK, Im JS, Yim J, Park SH, Hong DH

  • KMID: 1992534
  • Korean J Obes.
  • 2007 Jun;16(2):76-85.
BACKGROUND: Obesity has a multifactorial etiology, in which economic status plays an important role. The association between economic status and obesity begins from the adolescent period. The association between obesity...
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The Long-term Oncological Outcome of a Sphincter-saving Resection and an Abdominoperineal Resection for Lower Rectal Cancer

Jung SH, Yu CS, Choi PW, Kim DD, Hong DH, Kim HC, Kim JC

Purpose: The oncological safety of a sphincter-saving resection (SSR) in lower rectal cancer is widely accepted, and both an abdominoperineal resection (APR) and a SSR are used in potentially curative...
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The Analysis of Academic Achievements of Students at Gachon Medical School

Park KH, Hong DH, Oh JH, Park YB, Shin DJ, Lee YD

  • KMID: 2306750
  • Korean J Med Educ.
  • 2006 Dec;18(3):289-296.
PURPOSE: The purpose of this study was to examine the academic achievement of the first year medical students at Gachon University of Medicine and Science based on their characteristics (i.e....
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Risk Factors and Oncologic Impact of Anastomotic Leakage after Rectal Cancer Surgery

Jung SH, Yu CS, Choi PW, Kim DD, Hong DH, Kim HC, Kim JC

  • KMID: 1835559
  • J Korean Soc Coloproctol.
  • 2006 Dec;22(6):371-379.
PURPOSE: Anastomotic leakage (AL) is a serious and life-threatening complication following rectal cancer surgery. The impact on long-term oncologic outcome in patients with AL is not clear. The aim of...
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