- B-cell translocation gene 2 positively regulates GLP-1-stimulated insulin secretion via induction of PDX-1 in pancreatic beta-cells
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Hwang SL, Kwon O, Kim SG, Lee IK, Kim YD
- KMID: 2154244
- Exp Mol Med.
- 2013 May;45(5):e25.
Glucagon-like peptide-1 (GLP-1) is a potent glucoincretin hormone and an important agent for the treatment of type 2 diabetes. Here we demonstrate that B-cell translocation gene 2 (BTG2) is a... -
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- A Family with Axenfeld-Rieger Syndrome: Report of the Clinical and Genetic Findings
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Yang HJ, Lee YK, Joo CK, Moon JI, Mok JW, Park MH
- KMID: 2363769
- Korean J Ophthalmol.
- 2015 Aug;29(4):249-255.
- doi: 10.3341/kjo.2015.29.4.249
PURPOSE: To describe clinical findings in a Korean family with Axenfeld-Rieger syndrome. METHODS: A retrospective review of clinical data about patients with diagnosed Axenfeld-Rieger syndrome. Five affected members of the family... -
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- Circadian regulation of low density lipoprotein receptor promoter activity by CLOCK/BMAL1, Hes1 and Hes6
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Lee YJ, Han DH, Pak YK, Cho S
- KMID: 1401756
- Exp Mol Med.
- 2012 Nov;44(11):642-652.
Low density lipoprotein receptor (LDLR) plays an important role in the cholesterol homeostasis. We examined the possible circadian regulation of LDLR and mechanism(s) underlying it. In mice, blood glucose and... -
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- Expression of Cdx-2 Homeobox Gene in Intestinal Metaplasia and Gastric Adenocarcinoma
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Paik CH, Han DS, Lee SH, Chung YW, Kim JP, Sohn JH, Hahm JS, Oh YH, Park YU
- KMID: 1113418
- Korean J Gastroenterol.
- 2004 Oct;44(4):186-192.
BACKGROUND/AIMS: The Cdx-1 and Cdx-2 genes are intestinal transcription factors that may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. The Cdx-1 and Cdx-2... -
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- CDX1 and CDX2 Expression in Intestinal Metaplasia, Dysplasia and Gastric Cancer
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Kang JM, Lee BH, Kim N, Lee HS, Lee HE, Park JH, Kim JS, Jung HC, Song IS
- KMID: 1777864
- J Korean Med Sci.
- 2011 May;26(5):647-653.
- doi: 10.3346/jkms.2011.26.5.647
Intestinal metaplasia (IM) has been regarded as a premalignant condition. However, the pathogenesis of IM is not fully understood. The aim of this study was to evaluate the role of... -
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