- Mechanisms of Asthma and Implications for Its Prevention and Treatment: A Personal Journey
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Holgate ST
- KMID: 2260276
- Allergy Asthma Immunol Res.
- 2013 Nov;5(6):343-347.
- doi: 10.4168/aair.2013.5.6.343
My research career has focused on the causes of asthma and its treatment. After establishing the key role that mast cells play in the inflammatory response in asthma, attention was... -
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- A Brief History of Asthma and Its Mechanisms to Modern Concepts of Disease Pathogenesis
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Holgate ST
- KMID: 2133803
- Allergy Asthma Immunol Res.
- 2010 Jul;2(3):165-171.
- doi: 10.4168/aair.2010.2.3.165
The original concept of asthma being primarily a disease of airways smooth muscle drove the development of bronchodilator drugs. However when it was realised that airway inflammation underpinned the disordered... -
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