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Role of histone deacetylase activity in the developing lateral line neuromast of zebrafish larvae

He Y, Mei H, Yu H, Sun S, Ni W, Li H

Histone deacetylases are involved in many biological processes and have roles in regulating cell behaviors such as cell cycle entry, cell proliferation and apoptosis. However, the effect of histone deacetylases...
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ATM modulates transcription in response to histone deacetylase inhibition as part of its DNA damage response

Jang ER, Choi JD, Park MA, Jeong G, Cho H, Lee JS

Chromatin structure has a crucial role in a diversity of physiological processes, including development, differentiation and stress responses, via regulation of transcription, DNA replication and DNA damage repair. Histone deacetylase...
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Coordinated transcriptional regulation of calmegin, a testis-specific molecular chaperon, by histone deacetylase and CpG methyltransferase

Kim DH, Shim JS, Kwon HJ

  • KMID: 1089460
  • Exp Mol Med.
  • 2005 Oct;37(5):492-496.
Calmegin is a testis-specific molecular chaperon playing a key role in spermatogenesis. However, the transcriptional regulatory mechanisms for calmegin expression are entirely unknown. Herein, we revealed that calmegin is transcriptionally...
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