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Airways are More Reactive to Histamine than to Methacholine in Patients with Mild Airway Hyperresponsiveness, Regardless of Atopy

Choi IS, Lee S, Kim DH, Chung SW, Lee YC, Cho JY, Lee WJ

BACKGROUND: The airway muscles from allergen-sensitized animals in vitro show a heightened response to histamine, but not to carbachol. This study investigated whether the airway responsiveness to histamine in...
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Histamine and spontaneously released mast cell granules ffect the cell growth of human hepatocellular carcinoma cells

Lampiasi N, Azzolina A, Montalto G, Cervello M

  • KMID: 1047079
  • Exp Mol Med.
  • 2007 Jun;39(3):284-294.
The role of mast cells in tumor growth is still controversial. In this study we analyzed the effects of both histamine and pre-formed mediators spontaneously released by mast cells on...
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