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Improvements in Intractable Lumbar and LowerExtremity Symptoms after Systemic Administration of Tocilizumab, an Anti-interleukin-6 Receptor Antibody

Sainoh T, Sainoh T, Orita S, Orita S, Miyagi M, Miyagi M, Suzuki-Narita M, Suzuki-Narita M, Sakuma Y, Sakuma Y, Oikawa Y, Oikawa Y, Kubota G, Kubota G, Sato J, Sato J, Shiga Y, Shiga Y, Fujimoto K, Fujimoto K, Eguchi Y, Eguchi Y, Koda M, Koda M, Aoki Y, Aoki Y, Akazawa T, Akazawa T, Furuya T, Furuya T, Nakamura J, Nakamura J, Takahashi H, Takahashi H, Maki S, Maki S, Inoue M, Inoue M, Kinoshita H, Kinoshita H, Norimoto M, Norimoto M, Sato T, Sato T, Sato M, Sato M, Suzuki M, Suzuki M, Enomoto K, Enomoto K, Takaoka H, Takaoka H, Mizuki N, Mizuki N, Hozumi T, Hozumi T, Tsuchiya R, Tsuchiya R, Kim G, Kim G, Otagiri T, Otagiri T, Mukaihata T, Mukaihata T, Hishiya T, Hishiya T, Ohtori S, Ohtori S, Inage K, Inage K

Study Design: Prospective cohort study (open-label, single-arm, and non-blinded). Purpose: This study aims to determine the effects of systemic administration of tocilizumab, an anti-interleukin-6 (IL-6) receptor antibody on refractory low back...
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Time-Course Changes in Bone Metabolism Markers and Density in Patients with Osteoporosis Treated with Romosozumab: A Multicenter Retrospective Study

Inage K, Orita S, Eguchi Y, Shiga Y, Koda M, Aoki Y, Kotani T, Akazawa T, Furuya T, Nakamura J, Takahashi H, Suzuki-Narita M, Maki S, Hagiwara S, Inoue M, Norimoto M, Kinoshita H, Sato T, Sato M, Enomoto K, Takaoka H, Mizuki N, Hozumi T, Tsuchiya R, Kim G, Otagiri T, Mukaihata T, Hishiya T, Ohtori S

Purpose: In this multicenter retrospective observational study, we examined the early effects of romosozumab in patients with severe osteoporosis in terms of time-course changes in bone metabolism marker, improvement in...
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