- Open Heart Surgery in Patient with Heparin-Induced Thrombocytopenia
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Song SW, Hong YS, Kwak YL, Ahn SK
- KMID: 1916156
- Korean J Thorac Cardiovasc Surg.
- 2002 Jun;35(6):475-478.
A 45 year old man was admitted for aggravated dyspnea, abdominal distension and poor oral intake.On Echocardiogram,mitral stenosis(severe),tricuspid regurgitaion(IV),and LA thrombus were diagnosed.We used heparin with continuous infusion for prevention... -
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- Cardiopulmonary Bypass in Patient with Heparin-Induced Thrombocytopenia Employing Recombinant Hirudin
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Chung WS, Park CH, Sim JY, Lee JW, Choi IC
- KMID: 2031572
- Korean J Anesthesiol.
- 2000 Aug;39(2):270-274.
- doi: 10.4097/kjae.2000.39.2.270
Heparin-induced thrombocytopenia (HIT) is a heparin-dependent antibody-mediated platelet activating syndrome frequently accompanying thrombocytopenia, thromboembolism. We experienced a case of cardiopulmonary bypass using hirudin, a direct thrombin inhibitor, in a patient... -
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- Antiplatelet Effect of Hirudin in a Rabbit Carotid Artery Eversion Model
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Cho HK, Kang S, Lee SH, Pack KR, Park SH, Shin GJ, Jang Y, Chung KH
- KMID: 2093726
- Korean Circ J.
- 1999 Oct;29(10):1121-1128.
- doi: 10.4070/kcj.1999.29.10.1121
BACKGROUND AND OBJECTIVES: Thrombin and its interaction with platelets play a pivotal role in arterial thrombus formation. Hirudin, an anticoagulant agent derived from medicinal leeches(Hirudo medicinalis), is a unique and... -
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- Basic Data for Reference Intervals in Koreans for Parameters Produced by Multiplate Platelet Function Analyzer
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Baik SY, Hong JM, Lim YA
- KMID: 2312224
- Lab Med Online.
- 2013 Oct;3(4):191-197.
BACKGROUND: The Multiplate analyzer (Dynabyte GmbH) has been recently introduced as a platelet function test for patients taking antiplatelet drugs. The study aimed at providing basic data for determining the... -
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- Thrombin promotes epithelial ovarian cancer cell invasion by inducing epithelial-mesenchymal transition
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Zhong YC, Zhang T, Di W, Li WP
- KMID: 2288534
- J Gynecol Oncol.
- 2013 Jul;24(3):265-272.
- doi: 10.3802/jgo.2013.24.3.265
OBJECTIVE: Over-expression of thrombin in ovarian cancer cells is associated with poor prognosis. In this study, we investigated the role of thrombin in inducing epithelial-mesenchymal transition (EMT) in SKOV3 epithelial... -
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