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Asymmetric Gray Matter Volume Changes Associated with Epilepsy Duration and Seizure Frequency in Temporal-Lobe-Epilepsy Patients with Favorable Surgical Outcome

Kim JS, Koo DL, Joo EY, Kim ST, Seo DW, Hong SB

BACKGROUND AND PURPOSE: This study aimed to estimate the changes in gray matter volume (GMV) and their hemispheric difference in patients with mesial temporal lobe epilepsy (MTLE) using a voxel-based...
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Psychiatric Symptoms in Temporal Lobe Epilepsy with Left Mesial Hippocampal Sclerosis

Jang H, Kim SH, Park SH, Choo IH, Kim SG

A 16-year-old woman was referred to us for depression and persistent suicidal and homicidal ideation. From 2010, the patient visited a neurologist due to recurrent grand mal epilepsy, auditory and...
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Hippocampal Atrophy Identified by Volumetric Measurement in Intractable Epilepsy Cases

Kang SH, Kim BC, Nam TS, Kim JT, Choi SM, Lee SH, Park MS, Kim MK, Cho KH

  • KMID: 2343403
  • J Korean Neurol Assoc.
  • 2011 Aug;29(3):192-198.
BACKGROUND: Recurrent seizures result in brain damage, but it is usually gradual, minimal, and difficult to observe by visual inspection of magnetic resonance images (MRIs). It is well known that...
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Clinical Factors Related With Response to Anti-epileptics in Temporal Lobe Epilepsy With Hippocampal Sclerosis

Yang HW, Lee W, Jung YT, Hwang TG, Kim SE

  • KMID: 2065661
  • J Korean Neurol Assoc.
  • 2008 May;26(2):104-109.
BACKGROUNDS: Temporal lobe epilepsy with hippocampal sclerosis (TLE-HS) is not always intractable to antiepileptic drugs (AEDs). To identify the responsiveness to AEDs and related clinical factors in TLE-HS, we performed...
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Increased Corpora Amylacea in the Intractable Temporal Lobe Epilepsy: Case Report

Choi KY, Koh EJ, Choi HY

  • KMID: 1904549
  • J Korean Neurosurg Soc.
  • 2003 Jul;34(1):61-64.
Hippocampal sclerosis is the most common abnormal pathologic substrate found in patients with intractable temporal lobe epilepsy. Histopathological findings of hippocampal sclerosis are characterized by the presence of neuronal cell...
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Epilepsy : Surgical Treatment

Hong SC

Interest in epilepsy surgery is getting more and more increased with the development of computer-EEG and neuroimaging technique. There is a definite subgroup of intractable epilepsy patients who can be...
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Hippocampus/Frontal Gyrus FLAIR Signal Intensity Ratio in Patients with Mesial Temporal Lobe Epilepsy

Shon YM, Hong SB, Lee EK, Tae WS, Seo DW, Shin WC

  • KMID: 2342950
  • J Korean Neurol Assoc.
  • 2002 Mar;20(2):153-163.
BACKGROUND: The typical MRI features of hippocampal sclerosis (HS) are volume loss and increased T2 weighted signal intensity. Hippocampal volumetry and T2 relaxometry are useful quantitative methods for presurgical diagnosis...
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The Relationship between Hippocampal Damage on MRI and Secondarily Generalized Tonic Clonic Seizures in Temporal Lobe Epilepsy : Quantitative and Qualitative MRI Study

Kim SE

  • KMID: 2333364
  • J Korean Epilepsy Soc.
  • 2001 Dec;5(2):131-136.
PURPOSE: It has been suggested that recurrent seizures may cause the hippocampal formation (HF) damage in temporal lobe epilepsy (TLE). To evaluate whether secondarily generalized tonic clonic seizure (SGTC) is...
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Hippocampal Sclerosis: Correlation of MR Imaging Findings

Kim YH, Chang KH, Park SW, Ko YW, Lee SH, Yu IK, Han MH, Lee SK, Chung CK

OBJECTIVE: Atrophy and a high T2 signal of the hippocampus are known to be the principal MR imaging findings of hippocampal sclerosis. The purpose of this study was to determine...
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Regional MRI Volumetry and Longitudinal Regional Volume Curve for Detecting Hippocampal Sclerosis in Temporal Lobe Epilepsy

Hong SB, Kwon HY, Tae WS, Paik CH, Kim TW, Seo DW, Kim BJ, Na DK, Byun HS

  • KMID: 2186027
  • J Korean Neurol Assoc.
  • 2001 Mar;19(2):125-131.
BACKGROUND: In order to improve MRI volumetry of hippocampus, we obtained the Longitudinal Regional Volume Curve (LRVC) of hippocampi and compared the sensitivity of LRVC with those of conventional hippocampal...
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Glutamate Receptor Subunits Gene Expression in Kainate-induced Temporal Lobe Epilpsy Model

Kim MK, Choi SM, Lee SH, Kim BC, Cho KH, Nam SC, Lee MC

  • KMID: 1812914
  • J Korean Neurol Assoc.
  • 2001 Jan;19(1):36-44.
BACKGROUND: There is considerable controversy about the exact molecular mechanisms of excitatory amino acid receptors in epileptogenesis. METHODS: We used in situ hybridization to examine the hybridization density (HD) of...
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Personality Evaluation of Intractable Epilepsy Patients and the Postsurgical Change

Choi SJ, Yi J, Kang Y, Seo DW, Hong SC, Hong SB

  • KMID: 1816452
  • J Korean Epilepsy Soc.
  • 1999 Dec;3(2):195-199.
BACKGROUND: Epilepsy patients may have a various whole gamut of psychological problems attending upon, in part or in whole, epileptic seizure focus. To investigate psychological problems related to epileptic focus...
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Difference and Correlation between Seizure Numbers during the First Year and the Second Year of Antiepileptic Drug Treatnent in Temporal Lobe Epilepsy with Mesial Temporal Sclerosis

Kim JS, Lee BI, Kim OJ, Kim SY, Kim DI

  • KMID: 1539061
  • J Korean Epilepsy Soc.
  • 1999 Jun;3(1):39-43.
PURPOSE: Determination of medical intractability is primarily essential for planning a surgical treatment of epolepsy. Questions regarding intractability include the optimum duration of adequate antiepileptic drug (AED) treatment and the...
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Relationship of Longitudinal Extent of Hippocampal Sclerosis to Clinical Characteristics, Hippocampal Neuronal Cell Loss and Dynorphin-Immunoreactivity Patterns in Intractable Temporal Lobe Epilepsy with Hippocampal Sclerosis

Kim JS, Kim JS, Kim SY, Seo JS

  • KMID: 1539058
  • J Korean Epilepsy Soc.
  • 1999 Jun;3(1):16-21.
PURPOSE: In mesial temporal lobe epilepsy (TLE). Hippocampl sclerosis (HS) is a pathologic substrate and characterized by significant neuronal loss and band-like synaptic reorganization in dentate inner molecular layer (DGIML)...
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Comparison of factors related to persistent aura in TLE patients after temporal lobectomy

Kwak KH, Kang JK, Ma HI, Lee SA, Choi CG, Lee JK

  • KMID: 2016303
  • J Korean Neurol Assoc.
  • 1998 Dec;16(6):820-825.
BACKGROUND: Persistent auras after temporal lobectomy may be bothersome to the patients even though they are seizure free. But most authors specifically are concerned about the seizure outcome itself. The...
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Clinical Usefulness of T2 Relaxometry in Temporal Lobe Epilepsy

Lee PH, Kim JY, Kim WJ, Chun YG, Kim DI, Lee BI

  • KMID: 2342718
  • J Korean Neurol Assoc.
  • 1998 Oct;16(5):639-643.
BACKGROUND: Quantitative measurement of hippocampal T2 relaxation time is an objective means of determining the frequency and severity of signal abnormalities. To evaluate the diagnostic properties of T2 relaxometry in...
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Synaptic Reorganization of Dentate Mossy Fibers and Expression of Calcium Binding Proteins in Hippocampal Sclerosis of Temporal Lobe Epilepsy

Kim SP, Kim SP, Cho SC, Cho YR, Jeon JM, Kang YN, Kwon KY, Chang ES

  • KMID: 1725386
  • Korean J Pathol.
  • 1998 May;32(5):328-336.
This study was designed to identify expression of calcium-binding proteins and synaptic reorganizations of dentate mossy fibers in hippocampal sclerosis of human temporal lobe epilepsy. Hippocampal neuronal density was quantitively...
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A Morphological Study of Synaptic Reorganization in Mossy Fibers of the Dentate Gyrus according to Hippocampal Sclerosis in Temporal Lobe Epilepsy: A Comparison of Intraoperative ECoG Findings for Tailored Resection

Son EI, Kim SP, Kim IM, Kim IH

  • KMID: 2067473
  • J Korean Neurosurg Soc.
  • 1997 Jul;26(7):895-902.
This study was carried out to identify synaptic reorganization by mossy fibers of epileptic dentate gyrus by Timm sulphide silver histochemistry and to investigate degree of synaptic reorganization according to...
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