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The optimal conditions to improve retrovirus-mediated transduction efficiency to NIH 3T3 cells

Lee JA, Lee KM, Lee HJ, Lee YJ, Kim DH, Lim JS, Park KD

PURPOSE: We tried to assess the optimal conditions to improve low transduction efficiency and their effect on target cells. METHODS: Cultured NIH 3T3 cells were incubated with retroviral vectors bearing an...
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Gene Transfer into Cultured Cardiac Myocytes Mediated by Retrovirus

Huh JE, Kim DK, Byun JH, Park SJ, Jeon ES, Choe YH, Jung EA, Gwon HC, Park SW, Kim JS, Lee SH, Hong KP, Park JE, Cosset FL, Seo JD, Lee WR

BACKGROUND: Transplantation of cardiac myocytes (CMs) into the injured heart emerges as a potential alternative for the treatment of heart failure. Genetic modification of CMs could enhance and/or modify its...
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