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Expression of Hepatocyte Hepatitis B Core Antigen and Hepatitis B Surface Antigen as a Marker in the Management of Chronic Hepatitis B Patients

Yim SY, Kim TH, Jun SS, Kim ES, Keum B, Seo YS, Yim HJ, Jeen YT, Chun HJ, Lee HS, Um SH, Kim CD, Won NH, Ryu HS

BACKGROUND/AIMS: We aimed to clarify the association of hepatitis B surface antigen (HBsAg)/hepatitis B core antigen (HBcAg) with the disease status and treatment response in patients with chronic hepatitis B...
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In vivo hepatitis B virus-neutralizing activity of an anti-HBsAg humanized antibody in chimpanzees

Kim SH, Oh HK, Ryu CJ, Park SY, Hong HJ

Previously, we constructed a humanized antibody (HuS10) that binds to the common a antigenic determinant on the S protein of HBV. In this study, we evaluated its HBV-neutralizing activity in...
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Clinical Outcomes of Delayed Clearance of Serum HBsAg in Patients with Chronic HBV Infection

Nam SW, Jung JJ, Bae SH, Choi JY, Yoon SK, Cho SH, Han JY, Han NI, Yang JM, Lee YS

BACKGROUND: Spontaneous delayed clearance of hepatitis B surface antigen (HBsAg) in patients with chronic HBV infection is a rare event. The aim of this study was to investigate the...
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Action Mechanism in Immunopathogenesis and Clearance of HBV

Im SJ, Sung YC

  • KMID: 760642
  • Korean J Hepatol.
  • 2006 Jun;12(2):154-162.
Hepatitis B virus (HBV) currently infects more than 400 million people worldwide and they are at risk of developing chronic liver disease, cirrhosis and hepatocellular carcinoma. The immune response to...
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HBV-specific CD8+ T cells for Sustained HBeAg Seroconversion after Lamivudine Therapy

Lee CK, Han KH, Suh JH, Cho YS, Won SY, Chon CY, Moon YM, Park IS

  • KMID: 760578
  • Korean J Hepatol.
  • 2005 Mar;11(1):34-42.
BACKGROUND/AIMS: Viral suppression of the hepatitis B virus (HBV) can be induced by lamivudine, but the relapse seen in many patients after cessation of lamivudine therapy is troublesome. We...
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