- The Degrees of Hepatocyte Cytoplasmic Expression of Hepatitis B Core Antigen correlate with Histologic Activity of Liver Disease in the Young Patients with Chronic Hepatitis B Infection
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Kim TH, Cho EY, Oh HJ, Choi CS, Kim JW, Moon HB, Kim HC
- KMID: 1781835
- J Korean Med Sci.
- 2006 Apr;21(2):279-283.
- doi: 10.3346/jkms.2006.21.2.279
Subcellular localizaton of HBcAg have been found to be related to the activity of liver disease and HBV replication. The aim of this study was to determine whether the degree... -
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- Intracellular Antibody Fragment Against Hepatitis B Virus X Protein Does Not Inhibit Viral Replication
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Jin YH, Hong SH, Kim K, Shin HJ, Park S
- KMID: 1381254
- Yonsei Med J.
- 2006 Oct;47(5):721-728.
- doi: 10.3349/ymj.2006.47.5.721
Replication of the hepatitis B virus is suppressed by deficiency of the X protein. Although several molecules that block cellular targets of X protein reduce the production of hepatitis B... -
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- Hepatitis B core antigen expression pattern predicts response to lamivudine therapy in patients with chronic hepatitis B
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Shi KD, Hwang SG, Choi JH, Hwang IJ, Yoon JH, Kim KI, Kwon CI, Hong SP, Park PW, Rim KS
- KMID: 760784
- Korean J Hepatol.
- 2008 Jun;14(2):197-205.
- doi: 10.3350/kjhep.2008.14.2.197
BACKGROUNDS/AIMS: Negative hepatitis B core antigen (HBcAg) staining in hepatocytes is indicative of viral replication by an active immune response. HBcAg is expressed mainly in the cytoplasm in patients... -
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- Development of Clevudine Resistance after Switching from Lamivudine in a Patient with Chronic Hepatitis B
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Koh KH, Kang CJ, Kim DH, Choi YW, Kim MJ, Cheong JY, Cho SW
- KMID: 783106
- Korean J Gastroenterol.
- 2008 Nov;52(5):325-328.
Clevudine is a nucleoside analog of the unnatural beta-L configuration which has potent antiviral activity against hepatitis B virus (HBV). Clevudine is expected to have similar pattern of resistance profile... -
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- Potential Efficacy of Pegylated Interferon-α and a Nucleos(t)ide Analogue as Combination Therapy for HBeAg-Positive Chronic Hepatitis B
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Wi CI, Kim WR, Gross JB, Stadheim L, Poterucha
- KMID: 2412051
- Gut Liver.
- 2016 Jul;10(4):611-616.
- doi: 10.5009/gnl14256
BACKGROUND/AIMS: Despite the potent suppression of the hepatitis B virus with modern antiviral agents, only a minority of HBeAg-positive patients achieve hepatitis B e antigen seroconversion. We aimed to explore... -
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- Comparison of VERSANT Hepatitis B Virus DNA 3.0 Assay with Digene Hybrid Capture II Hepatitis B Virus DNA Test in Relation to Clinical Status of Hepatitis B Virus
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Song EY, Hur M, Lee KM, Yun Y, Lee CH, Choi YS, Lee KA, Roh EY
- KMID: 1781550
- Korean J Lab Med.
- 2007 Dec;27(6):451-457.
- doi: 10.3343/kjlm.2007.27.6.451
BACKGROUND: Some differences exist among various Hepatitis B virus (HBV) DNA quantification assays due to lack of standardization and besides clinical usefulness has not been firmly elucidated in Korean... -
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- Factors affecting initial virologic response and emergence of resistant mutants after adefovir treatment in lamivudine-resistant chronic hepatitis B patients
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Cho JH, Cheong JY, Kang JK, Park JS, Lee MH, Lim NK, Hong SP, Kim SO, Yoo WD, Cho SW
- KMID: 1073330
- Korean J Hepatol.
- 2008 Mar;14(1):58-66.
- doi: 10.3350/kjhep.2008.14.1.58
BACKGROUND/AIMS: Adefovir dipivoxil (adefovir) effectively inhibits both wild-type and lamivudine-resistant hepatitis B virus (HBV) replication. The development of adefovir resistance is both delayed and infrequent compared with lamivudine resistance.... -
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