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Epidemiology and prevention of hepatitis B virus infection

Kwon SY, Lee CH

Hepatitis B virus (HBV) infection has been a major global cause of morbidity and mortality. The recognition of the problem led to a worldwide effort to reduce transmission of HBV...
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Resistance to Adefovir in Patients with Chronic Hepatitis B

Ryu SH, Chung YH

  • KMID: 938252
  • Korean J Hepatol.
  • 2006 Dec;12(4):484-492.
No abstract available.
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Personalized treatment of hepatitis B

Lok AS

There are seven approved drugs for treatment of hepatitis B. Professional guidelines provide a framework for managing patients but these guidelines should be interpreted in the context of the individual...
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Occult Hepatitis B Virus Infection in Chronic Hepatitis C

Jang JY, Park EJ

Occult HBV infection is defined as the presence of HBV DNA in the liver (with or without detectable or undetectable HBV DNA in the serum) of individuals testing negative for...
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Molecular Mechanisms of Hepatitis B Virus-associated Hepatocellular Carcinoma

Park NH, Chung YH

Hepatocellular carcinoma (HCC) is one of the most common malignant diseases in the world. The hepatitis B virus (HBV) replicates non-cytopathically in hepatocytes, and most of the liver injury associated...
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KASL clinical practice guidelines: management of chronic hepatitis B

The Korean Association for the Study of the Liver (KASL)

No abstract available.
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Analysis of the precore and core promoter DNA sequence in liver tissues from tients with hepatocellular carcinoma

Cho SW, Shin YJ, Hahm KB, Jin JH, Kim YS, Kim JH, Kim HJ

To investigate the role of mutant hepatitis B virus (HBV) in the development of hepatocellular carcinoma (HCC), 20 patients with HCC were studied for precore and core promoter mutations in...
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Occult Hepatitis B Virus Infection and Hepatocellular Carcinoma

Lee JJ, Kwon OS

Many studies have suggested that occult HBV infection has a substantial clinical relevance to hepatocellular carcinoma (HCC). Occult HBV infection is an important risk factor for the development of cirrhosis...
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Heterogeneous HBV mutants coexist in Korean hepatitis B patients

Keum WK, Kim JY, Kim JY, Chi SG, Hong JW, Kim SS, Ha JH, Kang IS

  • KMID: 754997
  • Exp Mol Med.
  • 1998 Jun;30(2):115-122.
Although many hepatitis B virus (HBV) mutants have been found in all open reading frames since the precore defective mutant was initially reported, systematic investigations of diverse HBV mutant populations in hepatitis...
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Options for the management of antiviral resistance during hepatitis B therapy: reflections on battles over a decade

Yim HJ, Hwang SG

Although much advancement has been achieved in the treatment of chronic hepatitis B, antiviral resistance is still a challenging issue. Previous generation antiviral agents have already developed resistance in a...
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Histiocytic necrotizing lymphadenitis: A clinico-pathologic study of 45 cases with in situ hybridization for Epstein-Barr virus and hepatitis B virus

Cho KJ, Lee SS, Khang SK

Forty-five cases of histiocytic necrotizing lymphadenitis (HNL) or Kikuchi-Fujimoto disease were reviewed clinico-pathologically and studied for Epstein-Barr virus (EBV) and hepatitis B virus (HBV) by in situ hybridization to assess...
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A fatal case of hepatitis B virus (HBV) reactivation during long-term, very-low-dose steroid treatment in an inactive HBV carrier

Bae JH, Sohn JH, Lee HS, Park HS, Hyun YS, Kim TY, Eun CS, Jeon YC, Han DS

Hepatitis B virus (HBV) may be reactivated after chemotherapy or immunosuppressive therapy, and therefore administration of antiviral agents before such treatment is recommended. Most reported cases of reactivation are associated...
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Occult Hepatitis B Virus Infection: Transmission and Reactivation

Song SH, Hwang SG

Occult HBV infection (OBI) is defined as presence of HBV DNA in the liver tissue in patients with serologically undetectable HBsAg. There are differences in virologic and serological profiles of...
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Influence of Transforming Growth Factor-beta1 Gene Polymorphism at Codon 10 on the Development of Cirrhosis in Chronic Hepatitis B Virus Carriers

Yu SK, Kwon OS, Jung HS, Bae KS, Kwon KA, Kim YK, Kim YS, Kim JH

Transforming growth factor (TGF)-beta1 is a key cytokine producing extracellular matrix. We evaluated the effect of TGF-beta1 gene polymorphism at codon 10 on the development of cirrhosis in patients with...
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KASL Clinical Practice Guidelines: Management of chronic hepatitis B

The Korean Association for the Study of the Liver (KASL)

No abstract available.
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Human Leukocyte Antigen Class II Association with Spontaneous Recovery from Hepatitis B Virus Infection in Koreans: Analysis at the Haplotype Level

Cho SW, Cheong JY, Ju YS, Oh DH, Suh YJ, Lee KW

It has been speculated that human leukocyte antigen (HLA) alleles are associated with the outcome of hepatitis B virus (HBV) infection although the data obtained from various populations have shown...
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Impact of prior lamivudine use on the antiviral efficacy and development of resistance to entecavir in chronic hepatitis B patients

Hwang JA, Kim KB, Yang MJ, Lim SG, Hwang JC, Cheong JY, Cho SW, Kim SS

BACKGROUND/AIMS: To determine the efficacies of entecavir (ETV) in nucleos(t)ide analogue (NA)-naive chronic hepatitis B (CHB) patients and in those with prior lamivudine (LAM) use who did not develop resistance. METHODS:...
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Inactive hepatitis B surface antigen carriers and intrafamilial tramsmission: results of a 10-year study

Demirturk , Demirdal T

BACKGROUND/AIMS: The aims of the present study were to determine the outcomes of inactive hepatitis B virus (HBV) surface antigen (HBsAg) carriers over a 10-year study period and to elucidate...
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Regression of esophageal varices during entecavir treatment in patients with hepatitis-B-virus-related liver cirrhosis

Jwa HY, Cho YK, Choi EK, Kim HU, Song HJ, Na SY, Boo SJ, Jeong SU, Kim BS, Lee BW, Song BC

Recent studies suggest that liver cirrhosis is reversible after administering oral nucleos(t)ide analogue therapy to patients with hepatitis B virus (HBV) infection. However, few studies have addressed whether esophageal varices...
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Comparison of VERSANT Hepatitis B Virus DNA 3.0 Assay with Digene Hybrid Capture II Hepatitis B Virus DNA Test in Relation to Clinical Status of Hepatitis B Virus

Song EY, Hur M, Lee KM, Yun Y, Lee CH, Choi YS, Lee KA, Roh EY

BACKGROUND: Some differences exist among various Hepatitis B virus (HBV) DNA quantification assays due to lack of standardization and besides clinical usefulness has not been firmly elucidated in Korean...
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