- Intracellular Antibody Fragment Against Hepatitis B Virus X Protein Does Not Inhibit Viral Replication
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Jin YH, Hong SH, Kim K, Shin HJ, Park S
- KMID: 1381254
- Yonsei Med J.
- 2006 Oct;47(5):721-728.
- doi: 10.3349/ymj.2006.47.5.721
Replication of the hepatitis B virus is suppressed by deficiency of the X protein. Although several molecules that block cellular targets of X protein reduce the production of hepatitis B... -
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- Monitoring and Treatment Strategy for Chronic Hepatitis B and Antiviral Resistant Hepatitis B
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Kim TY, Sohn JH
- KMID: 782870
- Korean J Gastroenterol.
- 2007 Jun;49(6):346-355.
Clinical management of chronic hepatitis B is rapidly evolving after the recent development of new antiviral drugs. These agents have been shown to be effective in improving virological, biochemical, and... -
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- Is tenofovir disoproxil fumarate an all-powerful weapon in the treatment of chronic hepatitis B?
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Kim JH, Lee JS
- KMID: 2129658
- Korean J Intern Med.
- 2015 Jan;30(1):23-26.
- doi: 10.3904/kjim.2015.30.1.23
No abstract available. -
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- Management of Antiviral Resistance in Chronic Hepatitis B
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Lim YS
- KMID: 2412184
- Gut Liver.
- 2017 Mar;11(2):189-195.
- doi: 10.5009/gnl15562
The primary goal of therapy for chronic hepatitis B (CHB) is to prevent liver disease progression. Hepatitis B surface antigen (HBsAg) seroclearance or seroconversion is regarded as an optimal endpoint... -
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- Management of Antiviral-Resistant Chronic Hepatitis B Virus Infection
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Yim HJ
- KMID: 1767539
- Korean J Gastroenterol.
- 2008 Jun;51(6):346-359.
Substantial progress has been made in the treatment of chronic hepatitis B during the past decade. Nucleos(t)ide analogues are now widely used due to their convenience, less side effects, and... -
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- Lamivudine Therapy for Korean Children with Chronic Hepatitis B
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Koh H, Baek SY, Chung KS
- KMID: 1786205
- Yonsei Med J.
- 2007 Dec;48(6):927-933.
- doi: 10.3349/ymj.2007.48.6.927
PURPOSE: Lamivudine is known to be very effective in suppressing hepatitis B virus replication and virus induced necroinflammation. The aim of this study was to evaluate lamivudine therapy efficacy,... -
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- Entecavir to Telbivudine Switch Therapy in Entecavir-Treated Patients with Undetectable Hepatitis B Viral DNA
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Kim DH, Choi JW, Seo JH, Cho YS, Won SY, Park BK, Jeon HH, Shin SY, Lee CK
- KMID: 2419112
- Yonsei Med J.
- 2017 May;58(3):552-556.
- doi: 10.3349/ymj.2017.58.3.552
PURPOSE: This study examined 2-year outcome of consecutive therapy using entecavir (ETV) followed by telbivudine (LdT) in subjects with undetectable hepatitis B virus (HBV) DNA level and normal alanine aminotransferase... -
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- Long-term virological outcome in chronic hepatitis B patients with a partial virological response to entecavir
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Jo YJ, Kim KA, Lee JS, Kim NH, Bae WK, Song TJ, Kim JW
- KMID: 2160681
- Korean J Intern Med.
- 2015 Mar;30(2):170-176.
- doi: 10.3904/kjim.2015.30.2.170
BACKGROUND/AIMS: The clinical outcome of patients with a partial virological response (PVR) to entecavir (ETV), in particular nucloes(t)ide analogue (NA)-experienced patients, has not been thoroughly investigated. The aim of the... -
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- Long-term efficacy of tenofovir disoproxil fumarate therapy after multiple nucleos(t)ide analogue failure in chronic hepatitis B patients
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Kim HJ, Cho JY, Kim YJ, Gwak GY, Paik YH, Choi MS, Koh KC, Paik SW, Yoo BC, Lee JH
- KMID: 2129661
- Korean J Intern Med.
- 2015 Jan;30(1):32-41.
- doi: 10.3904/kjim.2015.30.1.32
BACKGROUND/AIMS: The efficacy of tenofovir disoproxil fumarate (TDF) for the treatment of chronic hepatitis B (CHB) patients following prior treatment failure with multiple nucleos(t)ide analogues (NAs) is not well defined,... -
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- The efficacy of adefovir dipivoxil monotherapy and the incidence of genotypic resistance to adefovir dipivoxil in patients with lamivudine-resistant chronic hepatitis B infection
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Moon JH, Cho M, Yoon KT, Bae JH, Heo J, Kim GH, Kang DH, Song GA
- KMID: 1073302
- Korean J Hepatol.
- 2008 Dec;14(4):503-512.
- doi: 10.3350/kjhep.2008.14.4.503
BACKGROUND/AIMS: Adefovir dipivoxil (ADV) is a nucleotide analogue that inhibits wild-type hepatitis B virus (HBV) and lamivudine (LMV)-resistant HBV mutants. The aim of this study was to elucidate the... -
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- Clinical and Virologic Characteristics of Lamivudine Resistance in HBV-associated Chronic Liver Disease
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Kim SS, Chung MG, Ju KT, Park DK, Kwon OS, Koo YS, Kim YK, Choi DJ, Hwang YJ, Kim JH
- KMID: 863116
- Korean J Hepatol.
- 2002 Dec;8(4):405-417.
BACKGROUND/AIMS: Lamivudine therapy in chronic hepatitis B has been shown to be effective in inhibiting HBV replication. However, lamivudine resistance has been developed with prolonged use. We studied to... -
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