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Growth promotion of HepG2 hepatoma cells by antisense-mediated knockdown of glypican-3 is independent of insulin-like growth factor 2 signaling

Sung YK, Hwang SY, Farooq M, Kim JC, Kim MK

  • KMID: 1109313
  • Exp Mol Med.
  • 2003 Aug;35(4):257-262.
Glypican-3 (GPC3) encodes a cell-surface heparan-sulfate proteoglycan and its expression is frequently silenced in ovarian cancer, mesotheliomas, and breast cancer cell lines and ectopic expression of GPC3 inhibited the growth...
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