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Hepatitis C Virus and Antiviral Drug Resistance

Kim S, Han KH, Ahn SH

Since its discovery in 1989, hepatitis C virus (HCV) has been intensively investigated to understand its biology and develop effective antiviral therapies. The efforts of the previous 25 years have...
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Simeprevir-Based Triple Therapy with Reduced Doses of Pegylated Interferon α-2a Plus Ribavirin for Interferon Ineligible Patients with Genotype 1b Hepatitis C Virus

Tamai H, Ida Y, Kawashima , Shingaki N, Shimizu R, Moribata K, Nasu T, Maekita T, Iguchi M, Kato J, Nakao T, Kitano M

BACKGROUND/AIMS: The present study aimed to evaluate the safety and efficacy of simeprevir-based triple therapy with reduced doses of pegylated interferon (PEG-IFN) and ribavirin for interferon (IFN) ineligible patients, such...
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A 2015 roadmap for the management of hepatitis C virus infections in Asia

Lim SG, Dan YY

The prevalence of hepatitis C virus (HCV) in Asia is 0.5% to 4.7%, with three different genotypes predominating, depending on the geographic region: genotype 1b in East Asia, genotype 3...
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Effectiveness and Complications of Combination Therapy with Interferon Alpha and Ribavirin in Patients with Chronic Hepatitis C

Hwang SY, Lee HJ, Park KT, Kim KY, Lee SM, Park CW, Kim TO, Kim GH, Heo J, Kang DH, Song GA, Cho M, Cho BM

  • KMID: 782839
  • Korean J Gastroenterol.
  • 2007 Mar;49(3):166-172.
BACKGROUND/AIMS: The effectiveness of combination therapy with conventional or pegylated interferon alpha and ribavirin in patients with chronic hepatitis C is well understood. However, the profound investigation about complications of...
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