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Ex vivo generation of functional dendritic cells from mobilized CD34+ hematopoietic stem cells

Min YH, Lee ST, Choi KM, Chong SY, Kim HO, Hahn JS, Ko YW

The ability to generate dendritic cells (DCs) in sizeable numbers has enormous implications for the development of clinically-effective antigen presentation procedures for cancer immunotherapy. We evaluated the generation of immunostimulatory...
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Hemorrhagic Cystitis Following Allogeneic Hematopoietic Cell Transplantation

Lee GW, Lee JH, Choi SJ, Kim S, Seol M, Kim WK, Lee JS, Lee KH

We conducted a retrospective study to investigate the incidence, risk factors, and clinical features of hemorrhagic cystitis (HC) following allogeneic hematopoietic cell transplantation (allo-HCT). Adult patients who developed HC after...
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Myeloablative Treatment Supported by Autologous Stem Cell Infusion with Neuroblastoma

Ryu KH, Seoh JY, Jang PS, Kim CW, Koh SH, Shin HY, Ahn HS

Bcr-abl antisense oligodeoxynucleotides (AS-ODNs) have provided evidence of an antileukemia effect when tested in vitro against Philadelphia-positive cells. In order to investigate the efficacy of AS-ODNs as purging agents in...
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Cell cycling status of human cord blood CD34+ cells during ex vivo expansion is related to the level of very late antigen expression

Seoh JY, Park HY, Chung WS, Kim SC, Hahn MJ, Kim KH, Shin HY, Ahn HS, Park KW, Ryu KH

Very late antigen-4 (VLA-4), which binds to the extracellular matrix protein fibronectin, is an integrin molecule known to be modulated during mobilization of CD34+ cells, and to be involved in...
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