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Clinical Trials with Stem Cells in Digestive Diseases and Future Perspectives

Kim TI

Many techniques for isolation, expansion and handling of stem cells are being developed rapidly, and preclinical evidence has shown the possibility to use this technology for refractory diseases in the...
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Clinical application of stem cells in liver diseases

Bae SH

Most liver diseases lead to hepatic dysfunction with organ failure. Liver transplantation is the best curative therapy, but it has some limitations such as donor shortage, possibility of rejection, and...
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Developmental changes in hematopoietic stem cell properties

Copley MR, Eaves CJ

  • KMID: 2154274
  • Exp Mol Med.
  • 2013 Nov;45(11):e55.
Hematopoietic stem cells (HSCs) comprise a rare population of cells that can regenerate and maintain lifelong blood cell production. This functionality is achieved through their ability to undergo many divisions...
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Understanding of molecular mechanisms in natural killer cell therapy

Yoon SR, Kim TD, Choi I

Cancer cells and the immune system are closely related and thus influence each other. Although immune cells can suppress cancer cell growth, cancer cells can evade immune cell attack via...
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Evaluation of Stem Cell Components in Retrocorneal Membranes

Lee SH, Kim KW, Kim MK, Chun YS, Kim JC

The purpose of this study was to elucidate the origin and cellular composition of retrocorneal membranes (RCMs) associated with chemical burns using immunohistochemical staining for primitive cell markers. Six cases...
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Direct and Indirect Effects of Androgens on Survival of Hematopoietic Progenitor Cells In Vitro

Kim SW, Hwang JH, Cheon JM, Park NS, Park SE, Park SJ, Yun HJ, Kim S, Jo DY

Androgens remain a common treatment for certain type of anemia, based upon its myelostimulating effects; however, it has not been established whether androgens affect apoptosis of hematopoietic progenitor cells (HPCs)....
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Respiratory Viral Infections after Hematopoietic Stem Cell Transplantation in Children

Choi JH, Choi EH, Kang HJ, Park KD, Park SS, Shin HY, Lee HJ, Ahn HS

This study was performed to characterize respiratory viral infections in pediatric patients undergoing hematopoietic stem cell transplantation (HSCT). Study samples included 402 respiratory specimens obtained from 358 clinical episodes that...
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Increasing and Worsening Late Effects in Childhood Cancer Survivors during Follow-up

Han JW, Kim HS, Kim BS, Kwon SY, Shin YJ, Kim SH, Ko JH, Lyu CJ

Recent advances in childhood cancer treatment have increased survival rates to 80%. Two out of three survivors experience late effects (LEs). From a group of 241 survivors previously described, 193...
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