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Development of an Automated Image Analyzer for Microvessel Density Measurement in Bone Marrow Biopsies

Chung Y, Shin S, Shim H, Sohn JY, Lee DE, Lee H, Eom HS, Kim KG, Kong SY

Angiogenesis is important for the proliferation and survival of multiple myeloma (MM) cells. Bone marrow (BM) microvessel density (MVD) is a useful marker of angiogenesis and an increase in MVD...
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Effects of Quercetin Supplementation on Hematological Parameters in Non-Alcoholic Fatty Liver Disease: a Randomized, Double-Blind, Placebo-Controlled Pilot Study

Pasdar Y, Oubari F, Zarif MN, Abbasi M, Pourmahmoudi A, Hosseinikia M

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease which has become a public health concern. Since oxidative stress plays a crucial role in the pathogenesis of NAFLD,...
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Revision of Laboratory Testing Guidelines for Initial Diagnosis of Hematologic Neoplasms

Kim IS, Lee JY, Kong SY, Lee ST, Huh J, Nam MH, Kim M, Cho YU, Huh HJ, Song J, Park H

The standardization committee of the Korean Society for Laboratory Hematology revised laboratory testing guidelines in order that hematologic neoplasms could be diagnosed according to the revised 4th edition of WHO...
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Reference values of hematological and biochemical parameters in young-adult cynomolgus monkey (Macaca fascicularis) and rhesus monkey (Macaca mulatta) anesthetized with ketamine hydrochloride

Koo BS, Lee DH, Kang P, Jeong KJ, Lee S, Kim K, Lee Y, Huh JW, Kim YH, Park SJ, Jin YB, Kim SU, Kim JS, Son Y, Lee SR

Nonhuman primate models are valuable in biomedical research. However, reference data for clinical pathology parameters in cynomolgus and rhesus monkeys are limited. In the present study, we established hematologic and...
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Improved Survival of Cancer Patients Admitted to the Intensive Care Unit between 2002 and 2011 at a U.S. Teaching Hospital

Sauer CM, Dong J, Celi LA, Ramazzotti D

PURPOSE: Cancer patients are at increased risk of treatment- or disease-related admission to the intensive care unit. Over the past decades, both critical care and cancer care have improved substantially....
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Large Unstained Cell, Blast Suspect and Delta Neutrophil Index ll Analyzed with Automated Hematology Analyzer as Parameters for the Prediction of Acute Leukemia Relapse

Hwang N, Kim YK, Suh JS

BACKGROUND: Here we investigated the clinical utilities of blast suspect, large unstained cell (LUC), delta neutrophil index ll (DN ll), and delta neutrophil index l (DN l), analyzed in peripheral...
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Recommendation for the Peripheral Blood Cell Morphology Report

Kwon JA, Kim YG, Park G, Kim JM, Cho YU, Huh J, Kong SY, Han JY, Yoon SY

There is considerable heterogeneity in the peripheral blood smear reports across different diagnostic laboratories, despite following the guidelines published by the International Council for Standardization in Haematology (ICSH). As standardization...
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Dental Consultations and Treatment Pattern of Pediatric Inpatient in Severance Hospital

Song J, Lee K, Song JS, Kim SO, Lee J, Choi HJ

The purpose of this study was to analyze the dental consultation of pediatric inpatients to the department of pediatric dentistry in Yonsei University Severance Hospital, and to investigate the change...
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A Clue to Discovering Unstable Hemoglobin Variants via Abnormal WBC Differential Scattergrams Using the Sysmex Automated Hematology Analyzer

Park S, Jeong TD, Hong KS, Huh J

Incidentally, hemoglobin (Hb) variants can be detected using HbA1c tests in clinical laboratories. We found 38 patients with Hb variants after reviewing a total of 29,398 HbA1c test results from...
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Recent progress in laboratory diagnosis of thalassemia and hemoglobinopathy: a study by the Korean Red Blood Cell Disorder Working Party of the Korean Society of Hematology

Lee YK, Kim HJ, Lee K, Park SH, Song SH, Seong MW, Kim M, Han JY

Genetic hemoglobin disorders are caused by mutations and/or deletions in the α-globin or β-globin genes. Thalassemia is caused by quantitative defects and hemoglobinopathies by structural defect of hemoglobin. The incidence...
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Annual Report of the Korean Association of External Quality Assessment Service on Routine Hematology (2018)

Lee YK, Kim YM, Routine Hematology Program, Korean Association of External Quality Assessment Service

Two trials were conducted with proficiency tests for complete blood cell count (CBC) and blood cell morphology as part of the 2018 Routine Hematology Program of the Korean Association of...
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Triggers and Outcomes of Falls in Hematology Patients: Analysis of Electronic Health Records

Jung MK, Lee SM

PURPOSE: The goal was to use electronic health records to identify factors and outcomes associated with falls among patients admitted to hematology units. METHODS: This retrospective case-control study included data from...
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Effect of immune-enhancing enteral nutrition formula enriched with plant-derived n-3 fatty acids on natural killer cell activity in rehabilitation patients

Cho JM, Choi HS, Cho YS, Park SY, Kim DY, Lee JH

BACKGROUND/OBJECTIVES: Enteral nutrition formulas with immune-enhancing nutrients, such as n-3 fatty acids, may manage patients' nutritional status and pathophysiological processes. The aim of our study was to investigate natural killer...
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Safety and Biodistribution of Human Bone Marrow-Derived Mesenchymal Stromal Cells Injected Intrathecally in Non-Obese Diabetic Severe Combined Immunodefi ciency Mice: Preclinical Study

Quesada MP, García-Bernal D, Pastor D, Estirado A, Blanquer M, García-Hernández AM, Moraleda J, Martínez

BACKGROUND: Mesenchymal stromal cells (MSCs) have potent immunomodulatory and neuroprotective properties, and have been tested in neurodegenerative diseases resulting in meaningful clinical improvements. Regulatory guidelines specify the need to perform...
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Establishment and operation of a cooperative program to identify work-related acute myeloid leukemia in a general hospital

Jung J, Choi HR, Cho BS, Park S, Myong JP, Kang MY, Kim HJ

BACKGROUND: The purpose of this report is to introduce the occupational cancer surveillance system, implemented in June 2018, and to share the results of our cooperative program. METHODS: The cooperative program...
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Smudge cell percentage as a surrogate marker for ZAP-70 expression in patients with chronic lymphocytic leukemia

Al-Kahiry , Tawfik HS, Sharshira , Ghanem A, El-Gammal , Mikhael IL

BACKGROUND: This study aimed to evaluate the prognostic value of smudge cell percentage as a surrogate marker for zeta-chain-associated protein kinase 70 (ZAP-70) expression in chronic lymphocytic leukemia (CLL) patients. METHODS:...
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Syndecan-1 (sCD138) levels in chronic lymphocytic leukemia: clinical and hematological correlations

Sharma M, Tyagi S, Tripathi P, Seth T

BACKGROUND: Syndecan-1 (sCD138) has recently been suggested to predict the clinical course of early-stage chronic lymphocytic leukemia (CLL), but few studies have been reported. This study assessed the role of...
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Identification of Cystoisospora ohioensis in a Diarrheal Dog in Korea

Lee S, Kim J, Cheon DS, Moon EA, Seo DJ, Jung S, Shin H, Choi C

A 3-month-old female Maltese puppy was hospitalized with persistent diarrhea in a local veterinary clinic. Blood chemistry and hematology profile were analyzed and fecal smear was examined. Diarrheal stools were...
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Evaluation of thrombocytopenia in the hematology clinic: a case series from a large tertiary care center

Ravindran , Go RS, Reichard K, Marshall A

No abstract available.
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How much progress has Blood Research made since the change of the journal title in 2013

Huh S

BACKGROUND: Blood Research (formerly) was renamed 5 years ago. It aimed to identify the progress of the renamed journal at the international level based on journal metrics. METHODS: Journal metrics, including...
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