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Radioprotective potential of Costus afer against the radiation-induced hematological and histopathological damage in mice

Akomolafe IR, Chetty N

Purpose: This study investigated the possible radioprotective effect of Costus afer extract (CAE) on hematological and histopathological parameters of mice. Materials and Methods: Fifty-four male mice with mass between...
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Lipid-Lowering Efficacy and Safety of a New Generic Rosuvastatin in Koreans: an 8-Week Randomized Comparative Study with a Proprietary Rosuvastatin

Kim H, Lee CJ, Choi D, Kim BK, Kim IC, Kim JS, Ahn CM, Hong GR, Cho IJ, Shim CY, Lee SH

Objective: The aim of this study was to investigate whether a new generic rosuvastatin is non-inferior to a proprietary one in terms of lipid-lowering efficacy. We also evaluated its non-lipid...
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Metabolic Reprogramming of Macrophages in Atherosclerosis: Is It All about Cholesterol?

Yvan-Charvet L, Ivanov S

Hypercholesterolemia contributes to the chronic inflammatory response during the progression of atherosclerosis, in part by favoring cholesterol loading in macrophages and other immune cells. However, macrophages encounter a substantial amount...
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Comparison of Body Fluid Differential CountsUsing a Manual Counting Method oran Automated Hematology Analyzer

Lee J, Jeon K, Lee J, Kim M, Kim HS, Kang HJ, Lee YK

Background: Two methods of counting cells in body fluids were compared;manual counting using a Neubauer chamber, and automated cell countingusing an XN-350 hematology analyzer. Methods: Cells from 32 body fluid samples...
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Effects of Quercetin Supplementation on Hematological Parameters in Non-Alcoholic Fatty Liver Disease: a Randomized, Double-Blind, Placebo-Controlled Pilot Study

Pasdar Y, Oubari F, Zarif MN, Abbasi M, Pourmahmoudi A, Hosseinikia M

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease which has become a public health concern. Since oxidative stress plays a crucial role in the pathogenesis of NAFLD,...
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Reference values of hematological and biochemical parameters in young-adult cynomolgus monkey (Macaca fascicularis) and rhesus monkey (Macaca mulatta) anesthetized with ketamine hydrochloride

Koo BS, Lee DH, Kang P, Jeong KJ, Lee S, Kim K, Lee Y, Huh JW, Kim YH, Park SJ, Jin YB, Kim SU, Kim JS, Son Y, Lee SR

Nonhuman primate models are valuable in biomedical research. However, reference data for clinical pathology parameters in cynomolgus and rhesus monkeys are limited. In the present study, we established hematologic and...
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Improved Survival of Cancer Patients Admitted to the Intensive Care Unit between 2002 and 2011 at a U.S. Teaching Hospital

Sauer CM, Dong J, Celi LA, Ramazzotti D

PURPOSE: Cancer patients are at increased risk of treatment- or disease-related admission to the intensive care unit. Over the past decades, both critical care and cancer care have improved substantially....
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Large Unstained Cell, Blast Suspect and Delta Neutrophil Index ll Analyzed with Automated Hematology Analyzer as Parameters for the Prediction of Acute Leukemia Relapse

Hwang N, Kim YK, Suh JS

BACKGROUND: Here we investigated the clinical utilities of blast suspect, large unstained cell (LUC), delta neutrophil index ll (DN ll), and delta neutrophil index l (DN l), analyzed in peripheral...
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A Clue to Discovering Unstable Hemoglobin Variants via Abnormal WBC Differential Scattergrams Using the Sysmex Automated Hematology Analyzer

Park S, Jeong TD, Hong KS, Huh J

Incidentally, hemoglobin (Hb) variants can be detected using HbA1c tests in clinical laboratories. We found 38 patients with Hb variants after reviewing a total of 29,398 HbA1c test results from...
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Triggers and Outcomes of Falls in Hematology Patients: Analysis of Electronic Health Records

Jung MK, Lee SM

PURPOSE: The goal was to use electronic health records to identify factors and outcomes associated with falls among patients admitted to hematology units. METHODS: This retrospective case-control study included data from...
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How much progress has Blood Research made since the change of the journal title in 2013

Huh S

BACKGROUND: Blood Research (formerly) was renamed 5 years ago. It aimed to identify the progress of the renamed journal at the international level based on journal metrics. METHODS: Journal metrics, including...
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Effect of an Inpatient Rehabilitation Program for Recovery of Deconditioning in Hematologic Cancer Patients After Chemotherapy

Cha S, Kim I, Lee SU, Seo KS

OBJECTIVE: To investigate the effect of a rehabilitation program in terms of De Morton Mobility Index (DEMMI) score, in hematologic cancer patients after chemotherapy. METHODS: Hematologic cancer patients admitted for chemotherapy...
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Quality Management of Hematology Tests in Blood Center

Kim H, Hur M

The primary goal in transfusion medicine is to promote high standards of quality in all aspects of transfusion, including production, management, and transfusion of blood components. To achieve this goal,...
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Origins and History of Laboratory Medicine

Lee HJ, Oh SH, Chang CL

Medical diagnostics plays a significant role in clinical decisions. The first medical laboratory test to be developed was urine analysis, in which urine properties were analyzed for diagnosis. Urine analysis...
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The limited role of serum galactomannan assay in screening for invasive pulmonary aspergillosis in allogeneic stem cell transplantation recipients on micafungin prophylaxis: a retrospective study

Kim R, Koh Y, Shin DY, Choe PG, Kim NJ, Yoon SS, Oh MD, Park WB, Kim I

BACKGROUND: We evaluated the outcomes of serum galactomannan (GM) assay for the screening of invasive pulmonary aspergillosis (IPA) in allogeneic hematopoietic stem cell transplantation (alloHSCT) recipients while on primary antifungal...
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Hematologic and serum biochemical reference intervals of the Oriental white stork (Ciconia boyciana) and the application of an automatic hematologic analyzer

Han JI, Jang HJ, Na KJ

This study was conducted to establish accurate baseline values of clinical laboratory data with regard to age-related changes in the Oriental white stork (Ciconia boyciana). In addition, the availability of...
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Reference Intervals of Hematology and Clinical Chemistry Analytes for 1-Year-Old Korean Children

Lee HR, Shin S, Yoon JH, Roh EY, Chang JY

BACKGROUND: Reference intervals need to be established according to age. We established reference intervals of hematology and chemistry from community-based healthy 1-yr-old children and analyzed their iron status according to...
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Extracorporeal Life Support in Patients with Hematologic Malignancies: A Single Center Experience

Choi KB, Kim HW, Jo KH, Kim DY, Choi HJ, Hong SB

BACKGROUND: Extracorporeal life support (ECLS) in patients with hematologic malignancies is considered to have a poor prognosis. However, to date, there is only one case series reported in the literature....
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Reference values of clinical pathology parameters in cynomolgus monkeys (Macaca fascicularis) used in preclinical studies

Park HK, Cho JW, Lee BS, Park H, Han JS, Yang MJ, Im WJ, Park DY, Kim WJ, Han SC, Kim YB

Nonhuman primates are increasingly used in biomedical research since they are highly homologous to humans compared to other rodent animals. However, there is limited reliable reference data of the clinical...
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The Effect of Pulsatile Versus Nonpulsatile Blood Flow on Viscoelasticity and Red Blood Cell Aggregation in Extracorporeal Circulation

Ahn CB, Kang YJ, Kim MG, Yang S, Lim CH, Son HS, Kim JS, Lee SY, Son KH, Sun K

BACKGROUND: Extracorporeal circulation (ECC) can induce alterations in blood viscoelasticity and cause red blood cell (RBC) aggregation. In this study, the authors evaluated the effects of pump flow pulsatility on...
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