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Prescription Pattern of Intravenous Fosfomycin in a Provincial Hospital in Thailand

Thampithak A, Chaisiri K, Siangsuebchart O, Phengjaturat K, Aonjumras W, Hemapanpairoa J

Background: In Thailand, active antibiotics against Gram-negative bacteria are limited. The re-emergence of intravenous (IV) fosfomycin is an alternative. IV fosfomycin has broadspectrum activity, relative safety, and availability. The limitations...
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Optimizing the Dosing Regimens of Tigecycline against VancomycinResistant Enterococci in the Treatment of Intra-abdominal and Skin and Soft Tissue Infections

Santimaleeworagun W, Hemapanpairoa J, Changpradub D, Thunyaharn S

Tigecycline was previously considered to have activity against vancomycin-resistant Enterococcus (VRE) isolates, but the optimal dose was not clarified. Thus, this study assessed the in vitro activity of tigecycline against...
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Optimization of Linezolid Dosing Regimens for Treatment of VancomycinResistant Enterococci Infection

Santimaleeworagun W, Changpradub D, Hemapanpairoa J, Thunyaharn S

Background: Linezolid, an oxazolidinone antibiotic, is recommended for vancomycinresistant enterococci (VRE). However, 100% free-drug concentration above the minimum inhibitory concentration (fT>MIC) and an area under the curve of free drug...
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