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Characteristics and treatment patterns in older patients with locally advanced head and neck cancer (KCSG HN13-01)

Kang EJ, Lee YG, Keam B, Choi JH, Kim JS, Park KU, Lee KE, Kim HJ, Lee KW, Kim MK, Ahn HK, Shin SH, Lee JB, Kwon JH, Kim HR, Kim SB, Yun HJ

Background/Aims: Treatment decisions for locally advanced head and neck squamous cell carcinoma (LA-HNSCC) are complicated, and multi-modal treatments are usually indicated. However, it is challenging for older patients to complete...
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Mediastinal Lymph Node Metastasis from Head and Neck Cancer: Predictive Factors and Imaging Features

Ko IK, Yoon DY, Baek S, Hong JH, Yun EJ, Lee IJ

Purpose To assess the predictive factors and describe the imaging features of mediastinal lymph node (MLN) metastases in patients with head and neck cancer. Materials and Methods We compared the clinical...
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Carbon-ion radiotherapy in osteosarcoma of the mandible: a case report

Ha TW, Park S, Youn MY, Kim DW, Kim HJ

Carbon-ion radiotherapy (CIRT) is on the rise as a treatment choice for malignant tumor. Compared to conventional radiotherapy, particle beams have different physical and biological properties. Particle beam provides a...
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Outcomes and Biomarkers of Immune Checkpoint Inhibitor Therapy in Patients with Refractory Head and Neck Squamous Cell Carcinoma: KCSG HN18-12

Lee YG, Chang H, Keam B, Chun SH, Park J, Park KU, Shin SH, An HJ, Lee KE, Lee KW, Kim HR, Kim SB, Ahn MJ, Hwang IG

Purpose This study was conducted to determine the effectiveness of immune checkpoint inhibitors (ICIs) in recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC) after platinum-containing chemotherapy. We...
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Mucosa-Associated Lymphoid Tissue Lymphoma of the Cheek Mimicking Benign Entities: a Case Report

Hwang H, Shin JH, Ihn YK, Han S, Park HS

The prevalence of cheek lymphoma, especially a mucosa-associated lymphoid tissue lymphoma (MALT), is very rare. Non-specific symptoms and image findings of cheek lymphoma may mimic benign entities and make it...
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Targeting Fatty Acid Metabolism in Head and Neck Cancer

Kim JH, Ku M, Yang J, Byeon HK

Reprogramming of cellular metabolism is an important, emerging, and universal hallmark of cancer which has received considerable attention during the recent era of cancer research. Cancer cells show characteristic alterations...
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Association Between Interleukin-6 and Head and Neck Squamous Cell Carcinoma: A Systematic Review

Uz U, Eskiizmir G

Interleukin-6 (IL-6) is a proinflammatory cytokine which plays an important role in several regulatory mechanisms of cancer. Moreover, experimental and clinical studies have reported that IL-6 targeted therapies might provide...
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Clinicopathological Characteristics of H-Zone and Non-H-Zone Basal Cell Carcinoma in the Head and Neck Region

Shon U, Yeom K, Yun DK, Kim MH, Choi MS, Park BC

  • KMID: 2524128
  • Korean J Dermatol.
  • 2021 Dec;59(10):735-741.
Background: Basal cell carcinoma (BCC) is the most common type of skin cancer. However, limited comparative data on the characteristics and prognosis of BCC in the H-zone and non-H-zone exist. Objective:...
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A Case of Buccal Pilomatricoma Removed Through Intraoral Incision

Kim HD, Park MK, Lee HA, Ji YB

Pilomatricoma(or calcifying epithelioma) is a not common benign solitary tumor originated from outer root sheath cell of hair follicle or hair follicle of sebaceous glands. The tumor usually presents as...
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Reconstructive methods to resolve intractable fistulas that develop after radiation therapy in patients with head and neck cancer

Choi BH, Park SO, Ahn HC

Background: Radiation therapy (RT) is frequently used for supportive treatment and management of advanced head and neck cancers. This study performed a retrospective review of the treatment methods that were...
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Squamous cell carcinoma of head and neck: what internists should know

Jung K, Narwal M, Min SY, Keam B, Kang H

Squamous cell carcinoma of head and neck (SCCHN) is a group of cancer arising from mucosal surfaces of the head and neck. Optimal management of SCCHN requires a multidisciplinary team...
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Complex oncologic resection and reconstruction of the scalp: Predictors of morbidity and mortality

Tecce MG, Othman S, Mauch JT, Nathan S, Tilahun E, Broach RB, Azoury SC, Kovach SJ

Background: Oncologic resection of the scalp confers several obstacles to the reconstructive surgeon dependent upon patient-specific and wound-specific factors. We aim to describe our experiences with various reconstructive methods, and...
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A Case of Retropharyngeal Abscess Resulting from Infected Paratracheal Cyst

Lee ES, Park HS, Kim SH, Lee DK

A paratracheal cyst is an air-filled cyst lined by a ciliated epithelium, commonly referred to as a tracheal diverticulum. The most common location of paratracheal cysts is the right side...
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Prognostic implications of stromal hyaluronic acid protein expression in resected oropharyngeal and oral cavity cancers

Sun DS, Won HS, Hong SA, Hong JH, Jo H, Lee H, Kim O, Lee MA, Ko YH

Background/Aims: Hyaluronic acid (HA) regulates cell adhesion, migration and proliferation in various cancers. The clinical implications of HA in resected head and neck squamous cell carcinoma have not been elucidated....
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Free-flap reconstruction in recurrent head and neck cancer: A retrospective review of 124 cases

Kim HS, Chung CH, Chang YJ

Background: Free-flap reconstruction for recurrent head and neck cancer may be challenging depending on the previous treatments, those are, chemotherapy, radiotherapy, and surgery, including neck dissection or free tissue transfer....
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Aggressive cutaneous squamous cell carcinoma of the scalp

Suk S, Shin HW, Yoon KC, Kim J

Cutaneous squamous cell carcinoma (cSCC) is the second most common nonmelanoma skin cancer, and its incidence is increasing globally. In Korea, there were 12,516 diagnosed cases of cSCC between 1999...
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Local Metastatic Neck Cancer Involving the Distal Internal Carotid Artery Treated with En Bloc Resection and Arterial Reconstruction after Mandibular Osteotomy

Kontopodis N, Igoumenakis D, Mastorakis G, Logothetis I, Daskalakis N, Ioannou CV

Head and neck cancers represent an aggressive form of neoplastic diseases that warrant surgical resection, in order to achieve optimal outcomes. Moreover, the involvement of the carotid artery is associated...
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Impact of the Preoperative Neutrophil to Lymphocyte Ratio on Patients with Head and Neck Cancer

Kim GJ, Kang JM, Seo JH, Hwang SH, Youn HY, Jin HJ, Kang HR, Lee HH, Joo YH

Background and Objectives To investigate the prognostic value of the neutrophil to lymphocyte ratio (NLR) in patients with head and neck squamous cell cancer (HNSCC). Subjects and Method Clinical data from...
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Sequential reconstruction for recurrent head and neck cancer: A 10-year experience

Chung SW, Byun IH, Lee WJ

BACKGROUND: Most patients with head and neck cancer successfully undergo oncologic resection followed by free or local flap reconstruction, depending on the tumor’s size and location. Despite effective curative resection...
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Efficacy and safety of cisplatin and weekly docetaxel in patients with recurrent or metastatic squamous cell carcinoma of the head and neck

Kim MJ, Kim SM, Jung HA, Hong JY, Chang WJ, Choi MK, Kim HS, Sun JM, Park K, Ahn MJ

BACKGROUND/AIMS: We investigated the efficacy and toxicity of a weekly schedule of docetaxel and cisplatin as a first-line treatment in patients with recurrent or metastatic head and neck squamous cell...
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