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Observation of the Incidence of Acrosome Reaction in Human Spermatozoa Treated with Mibefradil as a T-type Ca2+i Channels Inhibitor

Lee JH, Lee IS, Kim YC, Son WY, Lee JH, Han CT

  • KMID: 2235708
  • Korean J Fertil Steril.
  • 2000 Mar;27(1):9-14.
OBJECTIVE : The sperm acrosome reaction is a Ca2+ -dependent exocytotic event that is triggered by adhesion to the mammalian egg's zona pellucida. Previous studies suggested a role of Ca2+...
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Expression of Heat Shock Protein HspA2 in Human Tissues

Son WY, Hwang SH, Han CT, Lee JH, Choi YJ, Kim S, Kim YC

  • KMID: 2235734
  • Korean J Fertil Steril.
  • 1999 Aug;26(2):225-230.
In mouse, the heat shock protein 70-2 (hsp70-2) is found to have special function in spermatogenesis. Based on the observation, the hypothesis that human hspA2 (human gene; 98.2% amino acid...
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Repression of HspA2 mRNA Expression in Human Testes with Abnormal Spermatogenesis

Son WY, Hwang SH, Han CT, Lee JH, Kim SJ, Kim YC

  • KMID: 2085123
  • Korean J Fertil Steril.
  • 1999 Apr;26(1):103-109.
OBJECTIVE: Heat shock protein 70-2 (Hsp70-2) gene knockout mice are found to have premeiotic arrest at the primary spermatocyte stage with a complete absence of spermatids and spermatozoa. This observation...
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Conservation of cis-Regulatory Element Controlling Timely Translation in the 3'-UTR of Selected Mammalian Maternal Transcripts

Lee HJ, Lim Y, Chang SH, Min K, Han CT, Hwang SY

  • KMID: 2166279
  • Genomics Inform.
  • 2007 Dec;5(4):174-178.
The earliest stages of mammalian embryogenesis are governed by the activity of maternally inherited transcripts and proteins. Cytoplasmic polyadenylation of selected maternal mRNA has been reported to be a major...
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Clinical Significance of Anti-HSP 70 Antibody in the Patients with Systemic Lupus Erythematosus

Lim JB, Kim HS, Park Q, Lee SK, Park YB, Han CT

  • KMID: 2031035
  • Korean J Clin Pathol.
  • 1999 Oct;19(5):548-553.
BACKGROUND: Heat shock proteins (HSPs), or stress proteins, are immunodominant antigens of many microorganisms. In this study, we have detected the anti-HSP 70 antibody and tried to explain the role...
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