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Recurrent Meningitis Caused by β-Lactamase-Positive Amoxicillin/ Clavulanate-Resistant Non-Typeable Haemophilus influenzae in a Child with an Inner Ear Malformation: A Case Report

Shin H, Kim G, Han SB, Jeong DC, Kang JH

Infections with Haemophilus influenzae type b have been decreasing due to widespread use of conjugate vaccines thereto, and there has been an increasing trend in the relative proportion of invasive...
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Trend of Antibiotic Susceptibility of Haemophilus influenzae Isolated from Children, 2014–2019

Lee E, Park S, Kim M, Lee J

Purpose: We investigated the trend of antibiotic susceptibility of Haemophilus influenzae over 5 consecutive years. Methods: We analyzed the antibiotic susceptibility of H. influenzae isolated from children aged
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Effects of Amniotic Membrane Extract on the Hyperplastic Response of the Middle Ear Mucosa in a Bacterially-Induced Otitis Media Rat Model: A Preliminary Study

Park JH, Kim HB, Ko SH, Kim BH, Lim YS, Park SW, Song JJ, Cho CG

Objectives. Human amniotic membrane extract (AME) is known to contain numerous bioactive factors and anti-inflammatory substances. However, the anti-inflammatory effects of AME on the middle ear (ME) mucosa are unclear....
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Isolated Sphenoid Sinusitis withNontypeable Haemophilus influenzae Bacteremia in a Healthy Child

Seok MJ, Choi KY, Shin S, Cho KY

Acute bacterial sinusitis is one of the most common diseases in children, and 5–13% of patients with viral upper respiratory infection experience secondary bacterial sinusitis as a complication. Isolated sphenoid...
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Evaluation of Antibodies Against Haemophilus influenzae Type b in Korean Adults

Lee JH, Kim HW, Lee S, Kim KH

PURPOSE: After the introduction of Haemophilus influenzae type b (Hib) vaccine in 1995 in Korea, it was included in the national immunization program in 2013. In the post-Hib vaccine era,...
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Sphenoid Sinusitis with Haemophilus influenzae Septicemia

Jeong W, Kim YA, Park Y

Haemophilus influenzae grows both aerobically and anaerobically and is an exclusively human pathogen. We present a case of septicemia originating from unilateral sphenoid sinusitis caused by non-typeable H. influenzae. No...
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A Clinical Study of Pediatric Bacterial Meningitis in Daejeon and Chungcheong area : 2006-2010

Park YJ, Chu CC, Kim JS, Kim SS, Kim YC, Kim WS, Yu J, Lee KS, Lee YH, Park HJ

  • KMID: 1815598
  • J Korean Child Neurol Soc.
  • 2013 Dec;21(4):241-249.
PURPOSE: The aim of this study was to investigate the causative organisms, clinical manifestations, and prognosis of pediatric patients with bacterial meningitis in Daejeon and Chungcheong area, occurred from 2006...
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Asymptomatic Bacteriuria Caused by Haemophilus influenzae in a Kidney Transplant Recipient

Kim HK, Ji M, Paek SM, An D, Sung H, Park SK, Kim MN

  • KMID: 2312201
  • Lab Med Online.
  • 2012 Jul;2(3):170-173.
Haemophilus influenzae has rarely been implicated as the causative agent of urinary tract infections (UTIs). However, cases of UTIs caused by H. influenza in patients with anatomical or functional urinary...
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Reduced Levofloxacin Susceptibility in Clinical Respiratory Isolates of Haemophilus Influenzae Is Not yet Associated with Mutations in the DNA Gyrase and Topoisomerase II Genes in Korea

Kim IS, Lee NY, Kim S, Ki CS, Kim SH

Among 155 clinical respiratory isolates of Haemophilus influenzae in Korea, 6 (3.9%) isolates had reduced levofloxacin susceptibility (MICs > or = 0.5 microg/mL). These six isolates had no significant quinolone...
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The Causative Organisms of Bacterial Meningitis in Korean Children in 1996-2005

Cho HK, Lee H, Kang JH, Kim KN, Kim DS, Kim YK, Kim JS, Kim JH, Kim CH, Kim HM, Park SE, Oh SH, Chung EH, Cha SH, Choi YY, Hur JK, Hong YJ, Lee HJ, Kim KH

Bacterial meningitis remains a serious cause of morbidity and mortality in childhood, despite the availability of effective vaccines against Haemophilus influenzae type b (Hib) or Streptococcus pneumoniae. The purpose of...
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Clinical Evaluation of the Multiplex PCR Assay for the Detection of Bacterial Pathogens in Respiratory Specimens from Patients with Pneumonia

Jung CL, Lee MA, Chung WS

BACKGROUND: Community-acquired pneumonia (CAP) is a major infectious disease with significant morbidity and mortality worldwide. Streptococcus pneumoniae, Haemophilus influenzae, Mycoplasma pneumoniae, Chlamydophila pneumoniae, Legionella pneumophila, and Bordetella pertussis are common...
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Bacterial meningitis in children experienced at a university hospital, 1993-2006

Cho SY, Kim TY, Lee H, Kim KH, Yoo ES, Kim HS, Park EA, Ryu KH, Seo JW, Sohn S, Lee SJ

PURPOSE: Despite the seriousness of bacterial meningitis in children, there is little information on the incidence, causative organisms, mortality rate and age distribution. We studied the frequency by age group...
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Cost-Benefit Analysis of Haemophilus Influenzae Type B Immunization in Korea

Shin S, Shin YJ, Ki M

An economic evaluation of Haemophilus influenzae type b (Hib) immunization was conducted to examine whether Hib immunization should be included in the Korea's national immunization program. The costs and benefits...
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Antibody prsistence after Haemophilus influenzae type b (Hib) primary vaccination and response to boosters in Korean children

Lee H, Park SE, Lim SY, Choi KM, Lee HJ, Kim KH

PURPOSE: Antibody persistence after primary series of Haemophilus influenzae type b (Hib) vaccine and responses to boosters are seldom studied in Korean children. We performed this study to evaluate the...
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A clinical study of child bacterial meningitis in Daejeon and Chungcheong area : 2001-2005

Lee YJ, Lee SJ, Park HJ, Lee YH, Kang SY, Kim YC, Lee IK, Lee KY, Lee KS, Kim WS

PURPOSE: The purpose of this study was to analyze the epidemiology, causative organism, clinical manifestation and prognosis of bacterial meningitis for children after the introduction of Haemophilus influenzae type b...
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Validation of enzyme immunoassay for the quantitative measurement of human IgG antibodies specific for Haemophilus influenzae Type b capsular polysaccharide

Kim KH, Lim SY

PURPOSE: This study was conducted to validate enzyme immunoassay (EIA) for the quantitative measurement of human IgG antibodies specific for Haemophilus influenzae type b (Hib) capsular polysaccharide. METHOD: We evaluated specificity,...
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In vitro antimicrobial activity of cefditoren against Streptococcus pneumoniae and Haemophilus influenzae clinical isolates

Kwak YG, Choo EJ, Park SJ, Lee JE, Jeong JY, Choi SH, Kim NJ, Kim YS, Woo JH, Ryu J

  • KMID: 2256476
  • Korean J Med.
  • 2007 Jan;72(1):68-73.
BACKGROUND: The aim of this study was to determine the in vitro activity of cefditoren, an oral third-generation aminothiazolyl cephalosporin, against Streptococcus pneumoniae and Haemophilus influenzae clinical isolates in a...
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Immunogenicity and Safety of a Combined Hepatitis B and Haemophilus influenzae Type b Conjugate(PRP-OMP) Vaccine(Comvaxâ„¢; Merck & Co.) in Korean Infants

Chung EH, Ma SH, Hong YJ, Kim KH, Kim JH, Lee JA, Lee HJ

PURPOSE: To reduce the number of injections necessary to vaccinate young infants, various combined vaccines have been developed. The Comvaxâ„¢ manufactured by Merck & Co. is a combination of Hepatitis...
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The Causative Organisms of Pediatric Bacterial Meningitis: A Single Center Experience from 1996 to 2005

Lee TJ, Chun JK, Kim DS

PURPOSE: We investigated the causative organisms of bacterial meningitis by age distribution from 1996 to 2005. METHODS: Retrospective data were obtained from the medical records with diagnosis of bacterial meningitis or...
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Present status and prospects of Haemophilus influenzae type b(Hib) immunization

Kim KH

Haemophilus influenzae type b(Hib) conjugate vaccines prevent Hib disease in individuals and reduce the carriage and transmission of the organism in the community. The incidence of Hib disease has been...
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