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4-Hexylresorcinol induced angiogenesis potential in human endothelial cells

Kim MK, Kim SG, Lee SK

Background 4-Hexylresorcinol (4HR) is able to increase angiogenesis. However, its molecular mechanism in the human endothelial cells has not been clarified. Methods As endothelial cells are important in angiogenesis, we treated the human...
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Aspirin-Triggered Resolvin D1 Inhibits TGF-β1-Induced EndMT through Increasing the Expression of Smad7 and Is Closely Related to Oxidative Stress

Shu Y, Liu Y, Li X, Cao L, Yuan X, Li W, Cao Q

The endothelial-mesenchymal transition (EndMT) is known to be involved in the transformation of vascular endothelial cells to mesenchymal cells. EndMT has been confirmed that occur in various pathologic conditions. Transforming...
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Morphine Attenuates Endothelial Cell Adhesion Molecules Induced by the Supernatant of LPS-Stimulated Colon Cancer Cells

Min TJ, Park SH, Ji YH, Lee YS, Kim TW, Kim JH, Kim WY, Park YC

A large reservoir of bacterial lipopolysaccharide (LPS) is available in the colon and this could promote colon cancer metastasis by enhancing tumor cell adhesion, intravasation, and extravasation. Furthermore, adhesion molecules...
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Epigallocatechin-3-gallate Regulates NADPH Oxidase Expression in Human Umbilical Vein Endothelial Cells

Ahn HY, Kim CH, Ha TS

Vascular NADPH oxidase plays a pivotal role in producing superoxide in endothelial cells and thus acts in the initiation and development of inflammatory cardiovascular diseases such as atherosclerosis. Epigallocatechin-3-gallate (EGCG),...
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Anti-cancer Activities of Ginseng Extract Fermented with Phellinus linteus

Lee JJ, Kwon HK, Jung IH, Cho YB, Kim KJ, Kim JL

In the present study, the anti-cancer effects of ginseng fermented with Phellinus linteus (GFPL) extract were examined through in vitro and in vivo assays. GFPL was produced by co-cultivating ginseng...
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Platelets Induce Proliferation of Human Umbilical Vein Endothelial Cells via CD154-CD40 Pathway Independently of VEGF

Cho W, Ko EM, Cheon IS, Jeoung DI, Kim YM, Choe J

BACKGROUND: Platelets take part in repairing the lesions of endothelial damage. To understand the molecular mechanism of this process, we tested the hypothesis that CD154 expressed on activated platelets stimulates...
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Development of Evaluating Ways for the Efficacy of Anti-VEGF Biopharmaceuticals

Nam EH, Jeon SH, Lee WJ, Seo DW, Kim PH

BACKGROUND: Angiogenesis mediated by VEGF constitutes a new target for anti-cancer therapy which has explored through different ways of intervention aiming at the blocking of the tumoral angiogenesis. In the...
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Characterization of the Expression of PKCalpha(Isoform) in DMH-induced Vascular Endothelial Proliferation

Nam SB, Bae YC, Park SY, Choi SJ

  • KMID: 2322377
  • J Korean Soc Plast Reconstr Surg.
  • 2007 Nov;34(6):679-684.
PURPOSE: DMH(1,2-dimethylhydrazine) has been known to induce vascular neoplasm such as malignant endothelioma in animal experiment, through induction of abnormal proliferation of HUVECs. In our previous studies, 11 types of...
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The expression of heat shock protein (hsp) 90 and 27 in human umbilical vein endothelial cell (HUVEC)

Kim SY, Choi CY, Kang HJ, Hwang YJ

  • KMID: 2141696
  • Korean J Obstet Gynecol.
  • 2006 May;49(5):1043-1050.
OBJECTIVE: To study for the expression of heat shock protein (hsp) 90 and hsp27 when human umbilical vein endothelial cell (HUVEC) was treat with heat shock and H2O2. METHODS: We...
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Preparation and Characterization of SDF-1alpha Recombinant Adenovirus for ex vivo Expansion of Hematopoietic Stem Cells

Joo EK, Jo DY, Joo JH, Myung PK, Lee Y

  • KMID: 2168480
  • J Bacteriol Virol.
  • 2005 Mar;35(1):39-47.
Stromal cell-derived factor 1 (SDF-1/CXCL12) is a multifunctional cytokine implicated in normal hematopoiesis. We previously reported that SDF-1alpha enhanced the survival of hematopoietic stem and progenitor cells in synergy with...
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Effects of Low Intensity Ultrasound on the Co-Culture of Human Osteoblastic Cells (SaOS-2) with Endothelial Cells (HUVEC)

Choo SK, Kim BJ

  • KMID: 2104902
  • J Korean Orthop Res Soc.
  • 2002 Oct;5(2):140-150.
PURPOSE: We investigated the effects of low intensity ultrasound on the co-culture of human osteoblastic cells with endothelial cells and analysed cell proliferation and growth factors that might be involved...
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Effect of VCAM-1 expression in human endothelial cells by proinflammatory cytokines

Chang YH, Park SK, Moon HB, Lee JD, Kim SW, Hwang OY, Hong HN, Cho YJ

  • KMID: 1907977
  • J Asthma Allergy Clin Immunol.
  • 1999 Apr;19(2):163-172.
BACKGROUND: The expression of adhesion molecules contribute to development of systemic diseases. Vascular cell adhesion molecule-l(VCAM-1) is an endothelial cell membrane glycoprotein that has been implicated in leukocyte/endothelial cell interactions...
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The expression of IL-8 and GROalpha/MGSA in HUVEC stimulated by the TNF-alpha and IL-1

Song JS, Shin MS, Ahn JH, Moon HS, Park SH

  • KMID: 2318198
  • Tuberc Respir Dis.
  • 1999 Mar;46(3):338-349.
Polymorphonuclear leukocytes(PMN) are the predominant inflammatory cells recruited in acute lung injury such as adult respiratory distress syndrome, pneumonia and also chronic lung disease such as idiopathic pulmonary fibrosis and...
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The effect of IL-13 on adhesion of eosinophils to vascular endothelial cells

Song SH, Kim KH, Moon HS, Song JS, Park SH

  • KMID: 2286075
  • J Asthma Allergy Clin Immunol.
  • 1999 Feb;19(1):31-41.
BACKGROUND: Infiltration of eosinophils and activated T cells into the airway is a characteristic feature of allergic inflammation such as asthma. IL-4 has been shown to mediate adhesion of eosinophils and T...
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Hyperoxia influences mRNA expression of cytokines in cultured human umbilical vein endothelial cells

Park MS, Wallace HM

High concentrations of oxygen, indispensable for the treatment of severe hypoxemia from neonatal as well as adult respiratory distress syndrome, increase the risk of oxygen toxicity. Biochemical mechanisms are lipid...
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Effect of cytokines on the expression of cell adhesion molecule and on the adhesion of melanoma cells to endothelial cells

Kim SJ, Kim NS, Lee JL

We examined the role of cell adhesion molecules (CAM) by which tumor cells bind to the endothelial cells using human umbilical vein endothelial cells (HUVEC) and cultured melanoma cells. Endothelial...
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