Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

more+
SELECT FILTER
 
Close

PUBLICATION DATE

19 results
Display

Exploring the beneficial role of telmisartan in sepsis-induced myocardial injury through inhibition of high-mobility group box 1 and glycogen synthase kinase-3β/nuclear factor-κB pathway

Jin Y, Wang H, Li J, Dang M, Zhang W, Lei Y, Zhao H

In the present experimental study, cecal ligation and puncture significantly increased the myocardial injury assessed in terms of excess release of creative kinase-MB (CK-MB), cardiac troponin I (cTnI), interleukin (IL)-6...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Ameliorative Effects of Nilotinib on CCl4 Induced Liver Fibrosis Via Attenuation of RAGE/HMGB1 Gene Expression and Oxidative Stress in Rat

Khanjarsim V, Karimi J, Khodadadi , Mohammadalipour A, Goodarzi M, Solgi G, Hashemnia

Nilotinib as a tyrosine kinase inhibitor has been recently used to improve the liver fibrosis process, but the exact mechanisms still require further clarification. In this study, we investigated the...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Down-Regulation of Serum High-Mobility Group Box 1 Protein in Patients with Pulmonary Tuberculosis and Nontuberculous Mycobacterial Lung Disease

Kim SY, Koh WJ, Park HY, Jeon K, Lee SY, Yim JJ, Shin SJ

BACKGROUND: Recently, increased levels of high-mobility group box 1 protein (HMGB1) have been identified in various inflammatory conditions and infections. However, no studies have evaluated the HMGB1 level in nontuberculous...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Genetic Predisposition of Polymorphisms in HMGB1-Related Genes to Breast Cancer Prognosis in Korean Women

Lee J, Choi J, Chung S, Park J, Kim JE, Sung H, Han W, Lee JW, Park SK, Kim MK, Ahn SH, Noh DY, Yoo KY, Kang D, Choi JY

PURPOSE: The high mobility group box 1 (HMGB1) protein has roles in apoptosis and immune responses by acting as a ligand for receptor for advanced glycation end products (RAGE), Toll-like...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Effects of Remifentanil on Expression of High Mobility Group Box 1 in Septic Rats

Seo KH, Choi JW, Jung HS, Yoo H, Joo JD

High mobility group box 1 (HMGB1) is a pivotal mediator of sepsis progression. Remifentanil, an opioid agonist, has demonstrated anti-inflammatory effects in septic mice. However, it is not yet known...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Dimethyl Cardamonin Exhibits Anti-inflammatory Effects via Interfering with the PI3K-PDK1-PKCalpha Signaling Pathway

Yu WG, He H, Yao JY, Zhu YX, Lu YH

Consumption of herbal tea [flower buds of Cleistocalyx operculatus (Roxb.) Merr. et Perry (Myrtaceae)] is associated with health beneficial effects against multiple diseases including diabetes, asthma, and inflammatory bowel disease....
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Increase in the Level of Proinflammatory Cytokine HMGB1 in Nasal Fluids of Patients With Rhinitis and its Sequestration by Glycyrrhizin Induces Eosinophil Cell Death

Cavone L, Cuppari C, Manti S, Grasso L, Arrigo T, Calamai L, Salpietro , Chiarugi A

OBJECTIVES: The nuclear protein high mobility group protein box 1 (HMGB1) is a proinflammatory mediator that belongs to the alarmin family of proinflammatory mediators, and it has recently emerged as...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Eosinophils Modulate CD4+ T Cell Responses via High Mobility Group Box-1 in the Pathogenesis of Asthma

Shim EJ, Chun E, Lee HS, Bang BR, Cho SH, Min KU, Park HW

Eosinophils have been reported to modulate T cell responses. Previously, we reported that high-mobility group box 1 protein (HMGB1) played a key role in the pathogenesis of asthma. This study...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Role of High Mobility Group Box 1 in Innate Immunity

Lee SA, Kwak MS, Kim S, Shin JS

With growing accounts of inflammatory diseases such as sepsis, greater understanding the immune system and the mechanisms of cellular immunity have become primary objectives in immunology studies. High mobility group...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
HMGB1-Binding Heptamer Confers Anti-Inflammatory Effects in Primary Microglia Culture

Kim ID, Lee JK

High mobility group box 1 (HMGB1) is an endogenous danger signal molecule. In the postischemic brain, HMGB1 is massively released during NMDA-induced acute damage and triggers inflammatory processes. In a...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Current Understanding of HMGB1-mediated Autophagy

Kwak MS, Shin JS

Reactive oxygen species (ROS) is an oxidative stress to which cells respond by activating various defense mechanisms or cell death. Autophagy associated with oxidative stress response is a process to...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Toll-like receptor 4 on islet beta cells senses expression changes in high-mobility group box 1 and contributes to the initiation of type 1 diabetes

Li M, Song L, Gao X, Chang W, Qin X

Type 1 diabetes mellitus is caused by the autoimmune destruction of beta cells within the islets. In recent years, innate immunity has been proposed to play a key role in...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Extracellular High-Mobility Group Box 1 is Increased in Patients with Behcet's Disease with Intestinal Involvement

Ahn JK, Cha HS, Bae EK, Lee J, Koh EM

High-mobility group box 1 (HMGB1) protein has been demonstrated to play an important role in chronic inflammatory diseases including rheumatoid arthritis, and systemic lupus erythematosus. This study investigated the association...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Hypoxia Activates Toll-like Receptor 4 Signaling in Primary Mouse Hepatocytes Through the Receptor Clustering within Lipid Rafts

Kim DH, Billiar TR

PURPOSE: Transient hypoxia is an initial event that accentuates ischemia/reperfusion (I/R) injury in the liver. Hepatic ischemia/reperfusion (I/R) injury is largely related to innate immunity via Toll-like receptor 4 (TLR4)...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Sepsis Mortality in CIITA Deficient Mice is Associated with Excessive Release of High-mobility Group Box 1

Kim JY, Kim JH, Seo JN, Oh KI

BACKGROUND: Down regulation of major histocompatibility complex class II transactivator (CIITA) has been identified as a major factor of immunosuppression in sepsis and the level of CIITA expression inversely correlates...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Extracellular HMGB1 Released after Zinc-treatment Induces Neuronal Death in Primary Cortical Cultures

Lim CM, Kim JB, Lee JK

  • KMID: 2092922
  • Korean J Anat.
  • 2008 Mar;41(1):89-96.
As a nonhistone DNA-binding protein, high mobility group box 1 (HMGB1) is released in large amounts into the extracellular space immediately after ischemic insult and plays a role in the...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Role of HMGB1 and the Effect of Ethyl Pyruvate on Ischemia and Reperfusion Injury of Rat Kidney

Chung KY, Park JJ, Kim YS

  • KMID: 2201877
  • J Korean Soc Transplant.
  • 2007 Dec;21(2):234-240.
PURPOSE: High mobility group box-1 (HMGB1) was identified as a DNA binding protein that functions as a co-factor for proper transcriptional regulation in somatic cells. Extra- cellular HMGB1 acts as...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Proinflammatory Effects of High Mobility Group B1 (HMGB1) Versus LPS and the Mechanism of IL-8 Promoter Stimulation by HMGB1

Jeon EJ, Kwak HW, Song JH, Lee YW, Chung JW, Choi JC, Shin JW, Park IW, Choi BW, Kim JY

BACKGROUND: High mobility group box 1 (HMGB1) is a novel, late mediator of inflammation. This study compared the pro-inflammatory effects of LPS and HMGB1. The transcriptional factors that play an...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effects of HMGB-1 Overexpression on Cell-Cycle Progression in MCF-7 Cells

Yoon S, Lee JY, Yoon BK, Bae DS, Choi DS

High mobility group-1 (HMGB-1) enhances the DNA interactions and possesses a transcriptional activation potential for several families of sequence-specific transcriptional activators. In order to examine the effect of HMGB-1 on...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr