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Clinical Spectrum and Prognostic Factors of Acute Necrotizing Encephalopathy in Children

Seo HE, Hwang SK, Choe BH, Cho MH, Park SP, Kwon S

This study was conducted to investigate the etiology, the clinical characteristics and prognosis of acute necrotizing encephalopathy (ANE) in Korean children. Six children (1 yr to 7 yr) patients with...
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Is There Any Relationship Between Human Leucocyte Antigen Class II and Chronic Urticaria? (Chronic Urticaria and HLA Class II)

Oztas P, Onder M, Gonen S, Oztas MO, Soylemezoglu O

Human Leukocyte Antigen (HLA) typing of large groups of patients with various autoimmune diseases has demonstrated that some HLA alleles occur at higher frequencies in specific diseases than in the...
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Increased Prevalence of Autoimmune Thyroid Disease in Patients with Type 1 Diabetes

Park YS, Kim TW, Kim WB, Cho BY

  • KMID: 759519
  • Korean J Intern Med.
  • 2000 Dec;15(3):202-210.
BACKGROUND: Type 1 diabetes mellitus is frequently associated with other autoimmune diseases. The occurrence of common features of autoimmune diseases and the coassociation of multiple autoimmune diseases in the same...
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Association of HLA-DR and -DQ Genes with Familial Moyamoya Disease in Koreans

Hong SH, Wang KC, Kim SK, Cho BK, Park MH

OBJECTIVE: Moyamoya disease (MMD) is an uncommon cerebrovascular disorder, characterized by progressive occlusion at the terminal portion of the internal carotid artery. Incidence of the disease is high in East...
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Immunophenotypes and Proliferative Function of Lymphocytes in Umbilical Cord Blood

Yang YS, Kim DW

  • KMID: 2089513
  • Korean J Clin Pathol.
  • 1998 Jun;18(2):250-254.
BACKGROUND: The umbilical cord blood (UCB) is highlighted to be a alternative source of hematopoietic stem cells with a hope of resolving major problems of bone marrow transplantation, which are...
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Human Leukocyte Antigen Typing Proficiency Surveys in Korea, 2005-2006

Kim MH, Choi SE, Oh HB

BACKGROUND: To monitor the performance of histocompatibility testing laboratories, HLA proficiency survey in Korea has been conducted biannually since 1996. In this report, we summarized the results of the...
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A Study of Epstein-Barr Virus, and Human Leukocyte Antigen Typing in Children with Acute Infectious Mononucleosis

Hahn SH, Shin WS, Han H, Kang JH

  • KMID: 2335726
  • J Korean Pediatr Soc.
  • 2003 May;46(5):467-473.
PURPOSE: The Epstein-Barr virus(EBV), gamma herpesvirus, is an important pathogen that is widespread around the world. The EBV causes various diseases depending on the geographic location, and on the immunity...
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Estimation of the Prevalence of Adult - onset Insulin Dependent Diabetes Mellitus

Park YS, Lee KJ, Kim TW, Kim MH, Lee HK, Kim SY, Hoh CS, Min HK

  • KMID: 2080512
  • Korean J Med.
  • 1997 May;52(5):661-671.
OBJECTIVE: IDDM is an autoimmune disease, which occurs among genetically susceptible individuals. In the Asian populations, it is not uncommon for adult patients with NIDDM to eventually lose beta cell...
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The Role of HLA Class II Gene DQB1 in the Development of Duodenal Ulcer in Helicobacter pylori Infected Patients

Lee SJ, Chun HJ, Jeen YT, Lee HS, Song CW, Um SH, Lee SW, Choi JH, Kim CD, Ryu HS, Hyun JH, Jo YJ

  • KMID: 2038320
  • Korean J Gastroenterol.
  • 2002 Apr;39(4):254-259.
BACKGROUND/AIMS: Helicobacter pylori (H. pylori) infection is associated with gastroduodenal ulcer and gastric cancer only in a small proportion of infected subjects. Both virulence factors of H. pylori strains and...
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Sensitization to and Challenge with Gliadin Induce Pancreatitis and Extrapancreatic Inflammation in HLA-DQ8 Mice: An Animal Model of Type 1 Autoimmune Pancreatitis

Moon SH, Kim J, Kim MY, Park DH, Song TJ, Kim SA, Lee SS, Seo DW, Lee SK, Kim MH

BACKGROUND/AIMS: The aim of this study was to establish a pathogenetic mechanism of pancreatitis in celiac disease and IgG4-related disease using gluten-sensitive human leukocyte antigen (HLA)-DQ8 transgenic mice. METHODS: Transgenic mice...
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HLA-DQB1 Allele and Hypocretin in Korean Narcoleptics with Cataplexy

Jeong JH, Hong SC, Shin YK, Han JH, Lee SP

Cataplexy is one of the most pathognomonic symptoms in narcolepsy. This study was designed to investigate the frequency of the HLA-DQB1 allele and cerebrospinal fluid (CSF) hypocretin levels in Korean...
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Human Leukocyte Antigen Class II Association with Spontaneous Recovery from Hepatitis B Virus Infection in Koreans: Analysis at the Haplotype Level

Cho SW, Cheong JY, Ju YS, Oh DH, Suh YJ, Lee KW

It has been speculated that human leukocyte antigen (HLA) alleles are associated with the outcome of hepatitis B virus (HBV) infection although the data obtained from various populations have shown...
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Clinical Relevance of Pretransplant HLA Class II Donor-specific Antibodies in Renal Transplantation Patients with Negative T-cell Cytotoxicity Crossmatches

Song EY, Lee YJ, Hyun J, Kim YS, Ahn C, Ha J, Kim SJ, Park MH

BACKGROUND: We evaluated the clinical relevance of pretransplant donor-specific HLA antibodies (DSA) in renal transplantation patients who had negative T-cell cytotoxicity crossmatches. METHODS: From 328 consecutive renal transplant recipients, we selected...
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Use of PCR with Sequence-specific Primers for High-Resolution Human Leukocyte Antigen Typing of Patients with Narcolepsy

Woo HI, Joo EY, Hong SB, Lee KW, Kang ES

BACKGROUND: Narcolepsy is a neurologic disorder characterized by excessive daytime sleepiness, symptoms of abnormal rapid eye movement (REM) sleep, and a strong association with HLA-DRB1*1501, -DQA1*0102, and -DQB1*0602. Here, we...
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