- Screening for Barrett's Esophagus: Balancing Clinical Value and Cost-effectiveness
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Patel A, Gyawali CP
- KMID: 2449090
- J Neurogastroenterol Motil.
- 2019 Apr;25(2):181-188.
- doi: 10.5056/jnm18156
In predisposed individuals with long standing gastroesophageal reflux disease (GERD), esophageal squamous mucosa can transform into columnar mucosa with intestinal metaplasia, commonly called Barrett's esophagus (BE). Barrett's mucosa can develop... -
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- Esophageal Baseline Impedance From High-resolution Impedance Manometry Correlates With Mean Nocturnal Baseline Impedance From pH-impedance Monitoring
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Horton A, Sullivan B, Charles K, McIntosh T, Davis A, Gellad Z, Shimpi R, Gyawali CP, Patel A
- KMID: 2507111
- J Neurogastroenterol Motil.
- 2020 Oct;26(4):455-462.
- doi: 10.5056/jnm19142
Background/Aims Esophageal baseline impedance (BI) can be extracted from pH-impedance tracings as mean nocturnal baseline impedance (MNBI), and from high-resolution impedance manometry (HRIM), but it is unknown if values are similar... -
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- Patients With Definite and Inconclusive Evidence of Reflux According to Lyon Consensus Display Similar Motility and Esophagogastric Junction Characteristics
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Ribolsi M, Savarino E, Rogers B, Rengarajan A, Coletta MD, Ghisa M, Cicala M, Gyawali CP
- KMID: 2521157
- J Neurogastroenterol Motil.
- 2021 Oct;27(4):565-573.
- doi: 10.5056/jnm20158
Background/Aims The role of esophageal high-resolution manometry (HRM) within Lyon consensus phenotypes, especially patients with inconclusive gastroesophageal reflux disease (GERD) evidence, has not been fully investigated. In this multicenter, observational study... -
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- Nutrient Drink Test to Assess Gastric Accommodation in Cyclic Vomiting Syndrome: Single-blinded Parallel Grouped Prospective Study
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Kamal AN, Harris KB, Sarvapalli S, Sayuk GS, Gyawali CP, Gabbard S
- KMID: 2537941
- J Neurogastroenterol Motil.
- 2023 Jan;29(1):65-71.
- doi: 10.5056/jnm22013
Background/Aims Cyclic vomiting syndrome (CVS) is characterized by episodes of nausea and vomiting, separated by symptom-free intervals. The pathogenesis of CVS is poorly understood. Limited data exist on evaluating impaired gastric... -
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- Chronic Cough Is Associated With Long Breaks in Esophageal Peristaltic Integrity on High-resolution Manometry
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Bennett MC, Patel A, Sainani N, Wang D, Sayuk GS, Gyawali CP
- KMID: 2417382
- J Neurogastroenterol Motil.
- 2018 Jul;24(3):387-394.
- doi: 10.5056/jnm17126
BACKGROUND/AIMS: Breaks in the peristaltic contour on esophageal high-resolution manometry (HRM) may be associated with bolus retention in the esophagus. We evaluated the relationship between peristaltic breaks and esophageal symptoms,... -
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- High-resolution Manometry Determinants of Refractoriness of Reflux Symptoms to Proton Pump Inhibitor Therapy
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Ribolsi M, Savarino E, Rogers B, Rengarajan A, Coletta MD, Ghisa M, Cicala M, Gyawali CP
- KMID: 2507109
- J Neurogastroenterol Motil.
- 2020 Oct;26(4):447-454.
- doi: 10.5056/jnm19153
Background/Aims Impaired esophageal motility and disrupted esophagogastric junction (EGJ) on high-resolution manometry (HRM) have been associated with increased reflux severity in gastroesophageal reflux disease (GERD) patients. However, there are limited data... -
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- Transient Hiatal Separation During Straight Leg Raise Can Predict Reflux Burden in Gastroesophageal Reflux Disease Patients With Ineffective Esophageal Motility
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Lei WY, Liang SW, Omari T, Chang WC, Wong MW, Hung JS, Yi CH, Liu TT, Lin L, Gyawali CP, Chen CL
- KMID: 2534318
- J Neurogastroenterol Motil.
- 2022 Oct;28(4):589-598.
- doi: 10.5056/jnm21189
Background/Aims Straight leg raise (SLR) can be utilized to evaluate the integrity of the esophagogastric junction during high-resolution manometry (HRM). We aim to assess the value of transient hiatal separation during... -
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