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Dietary modulation of gut microbiota for the relief of irritable bowel syndrome

Kim MY, Choi SW

Irritable bowel syndrome (IBS) is a frequently diagnosed gastrointestinal (GI) disorder characterized by recurrent abdominal pain, bloating, and changes in the stool form or frequency without any structural changes and...
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Effect of gut microbiome on minor complications after a colonoscopy

Kim JH, Choi YJ, Kwon HJ, Jung K, Kim SE, Moon W, Park MI, Park SJ

Background/Aims: Minor complications that might occur after colonoscopy, including abdominal discomfort, bloating, diarrhea, and constipation, could a barrier for patients to undergo a screening colonoscopy. In this study, we aimed...
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Dysregulated Free Fatty Acid Receptor 2 Exacerbates Colonic Adenoma Formation in ApcMin/+ Mice: Relation to Metabolism and Gut Microbiota Composition

Huang YW, Lin CW, Pan P, Echeveste CE, Dong A, Oshima K, Yearsley M, Yu J, Wang LS

Free fatty acid receptor 2 (FFAR2) has been reported as a tumor suppressor in colon cancer development. The current study investigated the effects of FFAR2 signaling on energy metabolism and...
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Regulation of Gut Microbiota Disrupts the Glucocorticoid Receptor Pathway and Inflammation-related Pathways in the Mouse Hippocampus

Rao X, Liu L, Wang H, Yu Y, Li W, Chai T, Zhou W, Ji P, Song J, Wei H, Xie P

An increasing number of studies have recently indicated the important effects of gut microbes on various functions of the central nervous system. However, the underlying mechanisms by which gut microbiota regulate...
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Alteration of Gut Microbiota in Autism Spectrum Disorder: An Overview

Oh D, Cheon KA

  • KMID: 2504043
  • J Korean Acad Child Adolesc Psychiatry.
  • 2020 Jul;31(3):131-145.
  • doi: 10.5765/jkacap.190039
The microbiota-gut-brain axis, which refers to the bidirectional communication pathway between gut bacteria and the central nervous system, has a profound effect on important brain processes, from the synthesis of...
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The effect of curative resection on fecal microbiota in patients with colorectal cancer: a prospective pilot study

Park SS, Kim B, Kim MJ, Roh SJ, Park SC, Kim BC, Han KS, Hong CW, Sohn DK, Oh JH

Purpose: Although many studies have evaluated the association between intestinal microorganisms and the risk of colorectal cancer (CRC), only a few studies have investigated the changes in microorganisms following curative...
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Nonalcoholic fatty liver disease and alcohol-related liver disease: From clinical aspects to pathophysiological insights

Ikejima K, Kon K, Yamashina S

Two major causes of steatohepatitis are alcohol and metabolic syndrome. Although the underlying causes of alcoholrelated liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (NASH) differ, there are...
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Sex-related Alterations of Gut Microbiota in the C57BL/6 Mouse Model of Inflammatory Bowel Disease

Son HJ, Kim N, Song CH, Nam RH, Choi SI, Kim JS, Lee DH

BACKGROUND: Gut microbiota is closely associated with development and exacerbation of inflammatory bowel diseases (IBD). The aim of this study was to investigate differences in gut microbiota depending on sex...
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Downregulation of IL-18 Expression in the Gut by Metformin-induced Gut Microbiota Modulation

Lee H, Kim J, An J, Lee S, Choi D, Kong H, Song Y, Park IH, Lee CK, Kim K

IL-18 is a crucial pro-inflammatory cytokine that mediates chronic intestinal inflammation. Metformin, an anti-diabetic drug, was reported to have ameliorative effects on inflammatory bowel disease. Recently, the mechanism of action...
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Microbiome in the Gut-Skin Axis in Atopic Dermatitis

Lee SY, Lee E, Park YM, Hong SJ

The microbiome is vital for immune system development and homeostasis. Changes in microbial composition and function, termed dysbiosis, in the skin and the gut have recently been linked to alterations...
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Development and diversity of lactic acid producing bacteria and bifidobacteria in healthy full term Indian infants from Himachal Pradesh

Attri S, Mahajan R, Goel G

BACKGROUND/AIMS: The initial microbial colonization is a crucial step for the healthy development of an infant. Previous studies from India reported the dominance of target microbial species among Indian infants...
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The Roles of the Gut Microbiota and Toll-like Receptors in Obesity and Nonalcoholic Fatty Liver Disease

Miura K, Ishioka M, Iijima K

Obesity is characterized by low-grade chronic inflammation and is closely associated with the cardiovascular diseases, diabetes, and nonalcoholic fatty liver disease. Emerging data demonstrate that the gut microbiota contributes to...
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Gut Microbiota and Metabolic Disorders

Hur KY

The adult gut microbiota comprises 10~100 trillion microorganisms, which is equivalent to 10 times the number of total somatic and germ cells. Further, the collective genomes of gut microbiota (microbiome)...
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Clostridium difficile colonization and/or infection during infancy and the risk of childhood allergic diseases

Lee SH, Gong YN, Ryoo E

PURPOSE: The gut microbiota can influence several diseases through immune modulation; however, the exact role of microbes such as Clostridium difficileand the relationship between microbiota colonization and allergic diseases are...
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The Effect of Probiotics, Antibiotics, and Antipyretic Analgesics on Gut Microbiota Modification

Yun Y, Kim HN, Kim SE, Chang Y, Ryu S, Shin H, Woo SY, Kim HL

Human gut microbial community is playing a critical role in human health and associated with different human disease. In parallel, probiotics, antibiotics, and antipyretic analgesics (AAs) were developed to improve...
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Host-microbial Cross-talk in Inflammatory Bowel Disease

Nagao-Kitamoto H, Kamada N

A vast community of commensal microorganisms, commonly referred to as the gut microbiota, colonizes the gastrointestinal tract (GI). The involvement of the gut microbiota in the maintenance of the gut...
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The Curves Exercise Suppresses Endotoxemia in Korean Women with Obesity

Jin SA, Kim SK, Seo HJ, Kim M, Ahn KT, Kim JH, Park JH, Lee JH, Choi SW, Jeong JO

Obesity and metabolic syndrome is a worldwide pandemic and associated with high cardiovascular risk. Metabolic endotoxemia (ME) is thought to be an underlying molecular mechanism. It triggers toll-like receptor 4-mediated...
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Alterations in Gut Microbiota and Immunity by Dietary Fat

Yang BG, Hur KY, Lee MS

Gut microbiota play critical physiological roles in energy extraction from the intestine and in the control of systemic immunity, as well as local intestinal immunity. Disturbance of gut microbiota leads...
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Rapid Assessment of Microbiota Changes in Individuals with Autism Spectrum Disorder Using Bacteria-derived Membrane Vesicles in Urine

Lee Y, Park JY, Lee EH, Yang J, Jeong BR, Kim YK, Seoh JY, Lee S, Han PL, Kim EJ

Individuals with autism spectrum disorder (ASD) have altered gut microbiota, which appears to regulate ASD symptoms via gut microbiota-brain interactions. Rapid assessment of gut microbiota profiles in ASD individuals in...
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Pathogenic role of the gut microbiota in gastrointestinal diseases

Nagao-Kitamoto H, Kitamoto S, Kuffa P, Kamada N

The gastrointestinal (GI) tract is colonized by a dense community of commensal microorganisms referred to as the gut microbiota. The gut microbiota and the host have co-evolved, and they engage...
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