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Early Life Events and Development of Gut Microbiota in Infancy

Jeong S

With its dynamic composition and function, the gut microbiome plays a key role in human development and long-term health. The first 2 years of life are crucial to the early...
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The Gut Microbiome and Osteoarthritis: A Two-Sample Mendelian Randomization Study

Lee YH, Song GG

Objective: The aim of this study was to examine if the intestinal microbiome is causally correlated with osteoarthritis (OA) incidence. Methods: A two-sample Mendelian randomization (MR) study was conducted using...
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Lactobacillus attenuates progression of nonalcoholic fatty liver disease by lowering cholesterol and steatosis

Lee NY, Shin MJ, Youn GS, Yoon SJ, Choi YR, Kim HS, Gupta H, Han SH, Kim BK, Lee DY, Park TS, Sung H, Kim BY, Suk KT

Background/Aims: Nonalcoholic fatty liver disease (NAFLD) is closely related to gut-microbiome. There is a paucity of research on which strains of gut microbiota affect the progression of NAFLD. This study...
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Clinical Significance of Changes in Gut Microbiome Associated with Use of Proton Pump Inhibitors

Kim TJ, Lee H

Proton pump inhibitors (PPIs) are commonly used for the treatment of gastric acid-related disorders, and are generally well tolerated. However, by reducing the secretion of gastric acid in the long...
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The interaction between gut microbiome and nutrients on development of human disease through epigenetic mechanisms

Lee HS

Early environmental exposure is recognized as a key factor for long-term health based on the Developmental Origins of Health and Disease hypothesis. It considers that early-life nutrition is now being...
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Importance of nutritional therapy in the management of intestinal diseases: beyond energy and nutrient supply

Kim SE

The gut is an immune-microbiome-epithelial complex. Gut microbiome-host interactions have widespread biological implications, and the role of this complex system extends beyond the digestion of food and nutrient absorption. Dietary...
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Gut Microbiome, a Potent Modulator of Epigenetics in Human Diseases

Kim JA

Human physiology and pathology can be affected by different nutritional conditions. At cellular level, the availability of a nutritional component not only mediates metabolic reactions but also transmits signals for...
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Colonic Transit Time Is a Driven Force of the Gut Microbiota Composition and Metabolism: In Vitro Evidence

Tottey W, Feria-Gervasio D, Gaci N, Laillet B, Pujos E, Martin JF, Sebedio JL, Sion B, Jarrige JF, Alric M, Brugère J

  • KMID: 2367464
  • J Neurogastroenterol Motil.
  • 2017 Jan;23(1):124-134.
  • doi: 10.5056/jnm16042
BACKGROUND/AIMS: Human gut microbiota harbors numerous metabolic properties essential for the host's health. Increased intestinal transit time affects a part of the population and is notably observed with human aging,...
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