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Effect of Minocycline on Activation of Glia and Nuclear Factor kappa B in an Animal Nerve Injury Model

Gu EY, Han HS, Park JS

  • KMID: 1611424
  • Korean J Physiol Pharmacol.
  • 2004 Oct;8(5):237-243.
Glial cells are activated in neuropathy and play a key role in hyperalgesia and allodynia. This study was performed to determine whether minocycline could attenuate heat hyperalgesia and mechanical allodynia,...
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Effect of Minocycline on Nociceptive Change and Microglial Activation in a Rat Model of Sciatic Neuropathy

Gu EY, Han HS, Park JS

  • KMID: 2224500
  • Korean J Anat.
  • 2004 Aug;37(4):377-384.
Nerve injury leads to chronic neuropathic pain syndromes. Activation of microglia has been studied to investigate the role in pain development. Minocycline is known as a potent inhibitor of microglial...
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